Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | AHCY | P23526 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114115 | 0.84 | TBXAS1 (0.39) | TBXAS1TBXA2RHTR2AHTR2CHRH1 | |
| SCHEMBL11113224 | 0.83 | TBXAS1 (0.40) | TBXAS1TBXA2RHTR2AHTR2CHRH1 | |
| SCHEMBL11129673 | 0.83 | TBXAS1 (0.38) | TBXAS1HTR2AHTR2CHRH1 | |
| SCHEMBL11117014 | 0.83 | TBXAS1 (0.38) | TBXAS1AHCYHTR2AHTR2CHRH1 | |
| SCHEMBL11113630 | 0.82 | HTR2B (0.41) | TBXAS1TBXA2RHTR2AHTR2CHRH1 | |
| SCHEMBL11110382 | 0.81 | SMPD1 (0.42) | TBXAS1TBXA2RHTR2AHTR2C | |
| SCHEMBL11111976 | 0.78 | TBXAS1 (0.36) | TBXAS1HTR2AHTR2CHRH1 | |
| SCHEMBL11111420 | 0.78 | ALOX15 (0.40) | TBXAS1TBXA2RHTR2AHTR2CHRH1 | |
| SCHEMBL11114001 | 0.77 | MEN1 (0.40) | TBXAS1HTR2AHTR2CHRH1 | |
| SCHEMBL11113367 | 0.77 | ALDH1A1 (0.39) | TBXAS1HTR2AHTR2CHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038564-B1 | DIBENZ (B,E) OXEPIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | KYOWA HAKKO KOGYO CO., LTD (JP) | 1984-09-12 | — | — | EP | disclosed |
| US-4396550-A | ANTICHOLINERGIC, ANTIHISTIMINIC AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1983-08-02 | — | — | US | disclosed |