Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16351492 | 0.89 | MEN1 (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL49367 | 0.82 | TSHR (0.38) | TSHRPCSK9LTA4HPTGS2 | |
| SCHEMBL7788089 | 0.81 | TSHR (0.37) | TSHRPCSK9LTA4HPTGS2 | |
| SCHEMBL7944468 | 0.81 | TSHR (0.37) | TSHRPCSK9LTA4HPTGS2 | |
| SCHEMBL624569 | 0.80 | CYP3A4 (0.39) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL15658774 | 0.79 | TSHR (0.36) | TSHRPCSK9LTA4HPTGS2 | |
| SCHEMBL11474282 | 0.79 | CES2 (0.37) | TSHRPCSK9LTA4HPTGS2 | |
| Bromide SCHEMBL7610464 | 0.78 | CYP3A4 (0.38) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL6786715 | 0.77 | TSHR (0.35) | TSHRPCSK9LTA4HPTGS2 | |
| SCHEMBL6791527 | 0.77 | DNM1 (0.39) | MEN1KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040741-B1 | PROCESS FOR THE PREPARATION OF CHLOROFORMIC-ACID ARYL ESTERS | BAYER AG (DE) | 1983-06-08 | — | — | EP | disclosed |
| US-4366102-A | Process for the preparation of chloroformic acid aryl esters | BAYER AKTIENGESELLSCHAFT (DE) | 1982-12-28 | — | — | US | disclosed |
| EP-0040741-A1 | Process for the preparation of chloroformic-acid aryl esters | BAYER AG (DE) | 1981-12-02 | — | — | EP | disclosed |