Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14805182 | 0.83 | NPC1 (0.48) | HTTL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL16008105 | 0.82 | TSHR (0.51) | L3MBTL1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL657429 | 0.81 | ABCB1 (0.47) | ABCB1HTTL3MBTL1LMNASGMS2 | |
| SCHEMBL3822474 | 0.81 | L3MBTL1 (0.58) | HTTL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL377080 | 0.78 | ABCB1 (0.61) | ABCB1HTTL3MBTL1LMNASGMS2 | |
| SCHEMBL340937 | 0.77 | HTT (0.69) | HTTL3MBTL1SGMS2PTGER1MEN1 | |
| SCHEMBL6025409 | 0.77 | L3MBTL1 (0.45) | HTTL3MBTL1LMNAPTGER1MAPT | |
| SCHEMBL4431127 | 0.77 | SGMS2 (0.59) | ABCB1HTTL3MBTL1LMNASGMS2 | |
| SCHEMBL657253 | 0.77 | KDM4E (0.46) | ABCB1HTTL3MBTL1LMNASGMS2 | |
| SCHEMBL30535266 | 0.76 | SGMS2 (0.52) | ABCB1HTTL3MBTL1LMNASGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0037062-B1 | SUBSTITUTED 3-ARYL-2-CYCLOALKENE-1-ONES, PROCESS FOR THEIR PREPARATION AND THEIR PARMACEUTICAL USE | Beiersdorf Aktiengesellschaft (DE) | 1984-10-17 | — | — | EP | disclosed |
| US-4401831-A | ADRENOLYTIC AND HYPOTENSIVE AGENTS | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1983-08-30 | — | — | US | disclosed |
| US-4358460-A | HYPOTENSIVE, ANTIARRHYTHMIA, ANGINA PECTORIS | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1982-11-09 | — | — | US | disclosed |
| EP-0037062-A2 | Substituted 3-aryl-2-cycloalkene-1-ones, process for their preparation and their parmaceutical use | Beiersdorf Aktiengesellschaft (DE) | 1981-10-07 | — | — | EP | disclosed |