Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22498420 | 0.87 | SGMS2 (0.56) | SGMS2NPC1SMN1; SMN2HTTGAA | |
| SCHEMBL7331106 | 0.86 | NPC1 (0.51) | SGMS2NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL28862953 | 0.85 | NPC1 (0.56) | SGMS2NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL28790534 | 0.85 | FFAR4 (0.54) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL3679181 | 0.85 | SGMS2 (0.60) | SGMS2NPC1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL28256912 | 0.84 | MAOB (0.65) | NPC1RAB9AHPGDSMN1; SMN2HTT | |
| SCHEMBL3944560 | 0.84 | HTT (0.57) | SGMS2NPC1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL2999130 | 0.83 | SGMS2 (0.59) | SGMS2NPC1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL19156329 | 0.83 | SGMS2 (0.59) | SGMS2NPC1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL6243854 | 0.83 | NPC1 (0.64) | SGMS2NPC1RAB9AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061227-A | Environment-friendly ritodrine hydrochloride production method | GUANGDONG XIANQIANG PHARMACEUTICAL CO LTD | 2015-11-18 | — | — | CN | claimed |
| CN-101239917-B | Method for preparing ritodrine hydrochloride and intermediate thereof | Suzhou lixin pharmaceutical co ltd | 2011-05-04 | — | — | CN | claimed |
| CN-101239917-A | Method for preparing ritodrine hydrochloride and intermediate thereof | SUZHOU LIXIN PHARMACEUTICAL CO (CN) | 2008-08-13 | — | — | CN | claimed |
| CN-107787321-B | Novel5-HT2Antagonists | 安娜玛有限公司 | 2021-10-01 | — | — | CN | disclosed |
| WO-2020201305-A1 | 4-(2,4-BIS(2-HYDROXYPHENYL)-1H-IMIDAZOL-1-YL)BENZOIC ACID DERIVATIVES AS NOVEL IRON CHELATORS | VIFOR (INTERNATIONAL) AG (CH) | 2020-10-08 | — | — | WO | disclosed |
| WO-2020201305-A1 | 4-(2,4-BIS(2-HYDROXYPHENYL)-1H-IMIDAZOL-1-YL)BENZOIC ACID DERIVATIVES AS NOVEL IRON CHELATORS | VIFOR (INTERNATIONAL) AG (CH) | 2020-10-08 | — | — | WO | disclosed |
| EP-3310762-B1 | NOVEL 5-HT2 ANTAGONISTS | ANAMAR AB (SE) | 2020-08-05 | — | — | EP | disclosed |
| US-10544103-B2 | 5-HT2 antagonists | ANAMAR AB (SE) | 2020-01-28 | — | — | US | disclosed |
| US-20180155292-A1 | NOVEL 5-HT2 ANTAGONISTS | ANAMAR AB (SE) | 2018-06-07 | — | — | US | disclosed |
| EP-3310762-A1 | NOVEL 5-HT2 ANTAGONISTS | Anamar AB (SE) | 2018-04-25 | — | — | EP | disclosed |
| CN-105037180-B | Central analgesia noval chemical compound, the Preparation method and use of a kind of double action | 安徽省逸欣铭医药科技有限公司 | 2017-10-10 | — | — | CN | disclosed |
| CN-1349796-A | Pyrrole derivatives and medicine composition | NIPPON SHINYAKU CO LTD (JP) | 2002-05-22 | — | — | CN | disclosed |
| US-6268504-B1 | USED IN THE PRODUCTION OF PHARMACEUTICAL PRODUCTS | AMERICAN HOME PRODUCTS CORPORATION | 2001-07-31 | — | — | US | disclosed |
| CN-1186485-A | Pyrrole derivatives and pharmaceutical compositions | NIPPON SHINYAKU CO LTD (JP) | 1998-07-01 | — | — | CN | disclosed |
| EP-0123254-B1 | TRIAZINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-22 | — | — | EP | disclosed |
| EP-0116787-B1 | 1,1-DIPHENYLPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1987-03-18 | — | — | EP | disclosed |
| US-4618610-A | Triazine derivatives, and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-21 | — | — | US | disclosed |
| US-4605785-A | I(DUCE POLYSUBSTRATE MONOOXYGENASE ENZYME SYSTEM OF LIV)R WI HOUT GENTS | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1986-08-12 | — | — | US | disclosed |
| EP-0116787-A1 | 1,1-Diphenylpropanol derivatives, process for their preparation and pharmaceutical compositions containing them | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1984-08-29 | — | — | EP | disclosed |
| US-4111936-A | PYRIDAZINETHIONES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1978-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544103-B2 | 5-HT2 antagonists | HTR2B, HTR2C, HTR2A | SGMS2 3533/4885NPC1 3658/4885RAB9A 2274/4885 |
| US-20180155292-A1 | NOVEL 5-HT2 ANTAGONISTS | HTR2B, TPH2, HTR2C | SGMS2 3449/4885NPC1 3628/4885RAB9A 2314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.