Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337261 | 0.87 | SIGMAR1 (0.40) | HRH3HRH4ALDH1A1KDM4ETDP1 | |
| SCHEMBL4277270 | 0.69 | HRH3 (1.00) | HRH3HRH4ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL11329325 | 0.68 | ALDH1A1 (0.62) | HRH3HRH4ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL11193654 | 0.68 | HRH3 (0.50) | HRH3HRH4ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL11192716 | 0.68 | HRH3 (0.50) | HRH3HRH4ALDH1A1KDM4ECYP2D6 | |
| Hydrochloric Acid SCHEMBL11196289 | 0.67 | HRH3 (0.48) | HRH3HRH4ALDH1A1KDM4EHTT | |
| Hydrochloric Acid SCHEMBL7468055 | 0.67 | HRH3 (0.95) | HRH3HRH4ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL11201497 | 0.65 | HRH3 (0.94) | HRH3HRH4ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL23815516 | 0.65 | HRH3 (0.52) | HRH3HRH4ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL11194277 | 0.65 | ALDH1A1 (0.73) | HRH3HRH4ALDH1A1KDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58067667-A | — | — | None | — | — | JP | disclosed |
| JP-S5867667-A | 1-SUBSTITUTED-4-PHENYL-ISONICOPETINIC ACID ESTER | KAYAKU:KK | 1983-04-22 | — | — | JP | disclosed |