Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11132996 | 0.87 | HRH3 (0.52) | HRH3KDM4ETDP1ALDH1A1POLB | |
| SCHEMBL11844158 | 0.59 | MPO (0.70) | SIGMAR1MPOKDM4EALDH1A1LMNA | |
| SCHEMBL1415730 | 0.57 | SIGMAR1 (1.00) | SIGMAR1MC4RLMNADRD4KMT2A | |
| SCHEMBL242970 | 0.57 | SIGMAR1 (1.00) | SIGMAR1MC4RLMNADRD4KMT2A | |
| SCHEMBL1041303 | 0.57 | SIGMAR1 (1.00) | SIGMAR1MC4RLMNADRD4KMT2A | |
| SCHEMBL7989269 | 0.54 | LMNA (0.83) | SIGMAR1HRH3TDP1ALDH1A1LMNA | |
| SCHEMBL10690328 | 0.54 | LMNA (0.80) | SIGMAR1HRH3MC4RKDM4EALDH1A1 | |
| SCHEMBL11201497 | 0.53 | HRH3 (0.94) | HRH3KDM4EALDH1A1POLBCXCR4 | |
| SCHEMBL11666006 | 0.52 | — | — | |
| SCHEMBL4277270 | 0.51 | HRH3 (1.00) | HRH3KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323550-A | DENTISTRY PREVENTION OF CAVITIES | GOUPIL JEAN JACQUES | 1982-04-06 | — | — | US | disclosed |