Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AGER | Q15109 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722522 | 0.75 | TDP1 (0.44) | TDP1HTTHSD17B10MEN1HPGD | |
| SCHEMBL11497311 | 0.74 | TDP1 (0.39) | TDP1HTTHSD17B10MEN1HPGD | |
| SCHEMBL8412995 | 0.73 | MEN1 (0.47) | TDP1HTTHSD17B10MEN1HPGD | |
| SCHEMBL11451311 | 0.69 | TDP1 (0.46) | TDP1HTTAGERPOLBTNF | |
| SCHEMBL273486 | 0.69 | TDP1 (0.52) | TDP1HTTHSD17B10MEN1HPGD | |
| SCHEMBL8013907 | 0.69 | TDP1 (0.52) | TDP1HTTHSD17B10MEN1HPGD | |
| SCHEMBL1939000 | 0.68 | TDP1 (0.44) | TDP1HTTMEN1KMT2APOLB | |
| SCHEMBL11882314 | 0.67 | ASAH1 (0.48) | HTTHSD17B10MEN1HPGDKMT2A | |
| SCHEMBL1879818 | 0.66 | HTT (0.48) | TDP1HTTHSD17B10MEN1HPGD | |
| SCHEMBL3805246 | 0.66 | TDP1 (0.42) | TDP1HTTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006347-B1 | COMPOSITIONS AND METHOD FOR REGULATING SOYBEAN PLANT GROWTH UTILIZING SUBSTITUTED BENZAZOLYLTHIOALKANOIC ACIDS | MONSANTO COMPANY (US) | 1984-01-25 | — | — | EP | disclosed |