Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381049 | 0.77 | TDP1 (0.48) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL8013907 | 0.77 | TDP1 (0.52) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL273486 | 0.77 | TDP1 (0.52) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL16401979 | 0.74 | TDP1 (0.46) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL8413094 | 0.73 | APAF1 (0.55) | TDP1APAF1HTTSMN1; SMN2CYP11B1 | |
| SCHEMBL11497311 | 0.73 | TDP1 (0.39) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL11133096 | 0.73 | TDP1 (0.36) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL20683088 | 0.73 | TDP1 (0.48) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL9060998 | 0.73 | TDP1 (0.48) | MEN1HPGDKMT2AHSD17B10TDP1 | |
| SCHEMBL8413080 | 0.73 | TDP1 (0.48) | TDP1HTTSMN1; SMN2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859030-A | Substituted arylalkylthioalkylthiopyridines for use in the control of helicobacter bacteria | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-01-12 | — | — | US | disclosed |