Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | GNPAT | O15228 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61371 | 1.00 | ALOX15 (0.42) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| SCHEMBL61370 | 1.00 | ALOX15 (0.42) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| Water SCHEMBL6933673 | 0.98 | ALOX15 (0.41) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| Water SCHEMBL8680771 | 0.98 | ALOX15 (0.41) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| SCHEMBL7162439 | 0.98 | ALOX15 (0.41) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| SCHEMBL7162435 | 0.98 | ALOX15 (0.41) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| SCHEMBL27782979 | 0.94 | CTSS (0.39) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| SCHEMBL27782981 | 0.94 | CTSS (0.39) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| D-Alanine SCHEMBL7432397 | 0.93 | ALDH1A1 (0.40) | ALOX15KDM4EMAPTTHRBNFKB1 | |
| SCHEMBL11133973 | 0.92 | TNF (0.37) | ALOX15KDM4EMAPTTHRBNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689703-A1 | RESOLUTION OF 3-AMINO ALKYLNITRILES | Pfizer Products Inc. (US) | 2006-08-16 | — | — | EP | claimed |
| US-7026345-B2 | Resolution of 3-amino alkylnitriles | PFIZER INC. (US) | 2006-04-11 | — | — | US | claimed |
| US-20050107453-A1 | Resolution of 3-amino alkylnitriles | PFIZER INC. | 2005-05-19 | — | — | US | claimed |
| WO-2005040097-A1 | RESOLUTION OF 3-AMINO ALKYLNITRILES | PFIZER PRODUCTS INC. (US) | 2005-05-06 | — | — | WO | claimed |
| CN-116829949-A | Compositions for detecting or measuring analytes | 伯蒂斯有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116731106-A | Synthetic hexapeptide, composition and application thereof | 深圳市维琪科技股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-114569716-A | Reducing the viscosity of pharmaceutical formulations | 美国安进公司 | 2022-06-03 | — | — | CN | disclosed |
| EP-1689703-A1 | RESOLUTION OF 3-AMINO ALKYLNITRILES | Pfizer Products Inc. (US) | 2006-08-16 | — | — | EP | disclosed |
| US-7026345-B2 | Resolution of 3-amino alkylnitriles | PFIZER INC. (US) | 2006-04-11 | — | — | US | disclosed |
| US-20050107453-A1 | Resolution of 3-amino alkylnitriles | PFIZER INC. | 2005-05-19 | — | — | US | disclosed |
| WO-2005040097-A1 | RESOLUTION OF 3-AMINO ALKYLNITRILES | PFIZER PRODUCTS INC. (US) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107453-A1 | Resolution of 3-amino alkylnitriles | AADAT, AANAT, AAAS | ALOX15 1518/4885KDM4E 4055/4885MAPT 2731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.