SCHEMBL61370

SCHEMBL61370

CC(=O)NC(Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MAPT P10636 1/20 0.42
THRB P10828 1/20 0.42
NFKB1 P19838 1/20 0.42
PTGS2 P35354 1/20 0.42
THPO P40225 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ALDH1A1 P00352 1/20 0.41
TNF P01375 1/20 0.41
ITGB3 P05106 2/20 0.40
ITGA2B P08514 2/20 0.40
LMNA P02545 1/20 0.40
IDO1 P14902 1/20 0.36
TDO2 P48775 1/20 0.36
PPARG P37231 1/20 0.35
GNPAT O15228 1/20 0.35
CPB2 Q96IY4 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6026424 1.00 ALOX15 (0.42) ALOX15KDM4EMAPTTHRBNFKB1
SCHEMBL61371 1.00 ALOX15 (0.42) ALOX15KDM4EMAPTTHRBNFKB1
SCHEMBL7162435 0.98 ALOX15 (0.41) ALOX15KDM4EMAPTTHRBNFKB1
Water SCHEMBL6933673 0.98 ALOX15 (0.41) ALOX15KDM4EMAPTTHRBNFKB1
Water SCHEMBL8680771 0.98 ALOX15 (0.41) ALOX15KDM4EMAPTTHRBNFKB1
SCHEMBL7162439 0.98 ALOX15 (0.41) ALOX15KDM4EMAPTTHRBNFKB1
SCHEMBL27782981 0.94 CTSS (0.39) ALOX15KDM4EMAPTTHRBNFKB1
SCHEMBL27782979 0.94 CTSS (0.39) ALOX15KDM4EMAPTTHRBNFKB1
D-Alanine SCHEMBL7432397 0.93 ALDH1A1 (0.40) ALOX15KDM4EMAPTTHRBNFKB1
SCHEMBL11133973 0.92 TNF (0.37) ALOX15KDM4EMAPTTHRBNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1658 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
US-20260091067-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES MARVELBIOME INC (US) 2026-04-02 US claimed
US-20260026495-A1 STABLE PLASMIN COMPOSITIONS FOR ORGAN PRESERVATION AND RECONDITIONING GRIFOLS WORLDWIDE OPERATIONS LTD (IE) 2026-01-29 US claimed
US-20250258146-A1 QUANTITATIVE DETECTION METHOD OF MULTIPLE METABOLITES IN BIOLOGICAL SAMPLE AND METABOLIC CHIP HUMAN METABOLOMICS INSTITUTE INC. (CN) 2025-08-14 US claimed
EP-4587116-A2 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES MarvelBiome, Inc. (US) 2025-07-23 EP claimed
EP-3615069-B1 N-ACETYLATED AND NON-ACETYLATED DIPEPTIDES CONTAINING ARGININE TO REDUCE THE VISCOSITY OF VISCOUS COMPOSITIONS OF THERAPEUTIC POLYPEPTIDES AMGEN INC (US) 2025-05-28 EP claimed
WO-2025054048-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING LIPID AND CHOLESTEROL METABOLISM ASSOCIATED DISEASES, DISORDERS, AND CONDITIONS MarvelBiome, Inc. (US) 2025-03-13 WO claimed
CN-119584859-A Stable plasmin compositions for organ preservation and conditioning 基立福环球运营有限公司 2025-03-07 CN claimed
CN-114269951-B Diagnostic method for aesthetic deterioration of skin 欧莱雅 2024-12-27 CN claimed
EP-4440342-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING VAGUS NERVE ASSOCIATED DISEASES, DISORDERS, AND CONDITIONS MarvelBiome, Inc. (US) 2024-10-09 EP claimed
EP-0885019-B1 DUAL NEUTRALIZATION SYSTEM FOR IODINE TREATMENT OF CONTACT LENSES BAUSCH & LOMB (US) 2003-10-29 EP claimed
EP-1344515-A1 SKIN COSMETICS Shu Uemura Cosmetics Inc. (JP) 2003-09-17 EP claimed
US-6524593-B1 Alleviate or improve various cosmetic conditions and dermatological disorders, skin, hair, nails TRISTRATA, INC. 2003-02-25 US claimed
US-6159485-A COSMETICS; SKIN DISORDERS YUGENIC LIMITED PARTNERSHIP (US) 2000-12-12 US claimed
WO-2000040217-B1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS YUGENIC LIMITED PARTNERSHIP (US) 2000-10-05 WO claimed
EP-0620293-B1 Composition for treating copper or copper alloys MEC CO LTD (JP) 1997-01-15 EP claimed
WO-1996006639-A2 NOVEL DRUGS CONTAINING CHELATE-FORMING AGENTS MEDICO PHARMA VERTRIEBS GMBH (DE) 1996-03-07 WO claimed
US-5439783-A Consists of cupric complex of azole compound, an organic acid, a difficultly volatile complexing agent and water; used for surface treatment by oxidative etching MEC CO., LTD. (JP) 1995-08-08 US claimed
EP-0620293-A1 Composition for treating copper or copper alloys MEC CO., Ltd. (JP) 1994-10-19 EP claimed
WO-1993002689-A1 SYNTHETIC RIBONUCLEASES AND METHODS FOR PREPARING AND USING SAME UNIVERSITY OF MEDICINE & DENTISTRY (US) 1993-02-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260026495-A1 STABLE PLASMIN COMPOSITIONS FOR ORGAN PRESERVATION AND RECONDITIONING PLG, PLPBP, F2 ALOX15 3432/4885KDM4E 2283/4885MAPT 2186/4885
US-20260091067-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES IAPP, GPR119, FAHD1 ALOX15 2075/4885KDM4E 4749/4885MAPT 132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.