SCHEMBL11136157

SCHEMBL11136157

C=CN1CCCC1Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 1/20 0.41
MC4R P32245 2/20 0.40
MC3R P41968 2/20 0.40
MC1R Q01726 2/20 0.40
CCR3 P51677 1/20 0.40
SCD5 Q86SK9 1/20 0.40
GRIN2B Q13224 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7596029 0.95 SLC18A3 (0.43) SLC18A3
SCHEMBL3357498 0.94 SLC18A3 (0.42) SLC18A3
SCHEMBL4151234 0.83 MC4R (0.43) MC4RMC3RMC1RSCD5
SCHEMBL8416614 0.79 HSD11B1 (0.45)
SCHEMBL11463838 0.78 DRD2 (0.45)
SCHEMBL7592383 0.76 DPP4 (0.41)
SCHEMBL986930 0.76 CA1 (0.44) MC4R
SCHEMBL8565864 0.74 MC4R (0.46) SLC18A3MC4RMC3RMC1RCCR3
SCHEMBL5152847 0.74 MC4R (0.49) SLC18A3MC4RMC3RMC1RSCD5
SCHEMBL11466316 0.74 MC4R (0.46) SLC18A3MC4RMC3RMC1RCCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107743498-B Initiator for copolymerization of diene monomer and vinyl aromatic monomer 西索斯公司 2020-04-28 CN claimed
US-10584187-B2 Initiators for the copolymerisation of diene monomers and vinyl aromatic monomers SYNTHOS S.A. (PL) 2020-03-10 US claimed
EP-3280745-B1 INITIATORS FOR THE COPOLYMERISATION OF DIENE MONOMERS AND VINYL AROMATIC MONOMERS Synthos Sa (PL) 2018-12-12 EP claimed
US-20180072821-A1 INITIATORS FOR THE COPOLYMERISATION OF DIENE MONOMERS AND VINYL AROMATIC MONOMERS SYNTHOS S.A. (PL) 2018-03-15 US claimed
CN-107743498-B Initiator for copolymerization of diene monomer and vinyl aromatic monomer 西索斯公司 2020-04-28 CN disclosed
US-10584187-B2 Initiators for the copolymerisation of diene monomers and vinyl aromatic monomers SYNTHOS S.A. (PL) 2020-03-10 US disclosed
EP-3280745-B1 INITIATORS FOR THE COPOLYMERISATION OF DIENE MONOMERS AND VINYL AROMATIC MONOMERS Synthos Sa (PL) 2018-12-12 EP disclosed
US-20180072821-A1 INITIATORS FOR THE COPOLYMERISATION OF DIENE MONOMERS AND VINYL AROMATIC MONOMERS SYNTHOS S.A. (PL) 2018-03-15 US disclosed
US-4396698-A CROSSLINKED CATIONIC ADDITION COPOLYMERS AND HYDROPHOBIC PHENOLIC-TYPE COMPOUNDS; LIGHT SENSITIVE ELEMENTS FUJI PHOTO FILM CO., LTD. (JP) 1983-08-02 US disclosed