Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | DAGLA | Q9Y4D2 | 6/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 5/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4151234 | 0.95 | MC4R (0.43) | HSD11B1 | |
| SCHEMBL7596029 | 0.84 | SLC18A3 (0.43) | HSD11B1DAGLAABHD6 | |
| SCHEMBL3357498 | 0.83 | SLC18A3 (0.42) | HSD11B1DAGLAABHD6ATMPIK3C3 | |
| SCHEMBL16238876 | 0.80 | ALDH1A1 (0.49) | HSD11B1 | |
| SCHEMBL4143970 | 0.79 | SLC18A2 (0.55) | — | |
| SCHEMBL11136157 | 0.79 | SLC18A3 (0.41) | — | |
| SCHEMBL7469495 | 0.77 | HSD11B1 (0.45) | HSD11B1DAGLAABHD6DPP4ATM | |
| SCHEMBL6382268 | 0.76 | ABHD6 (0.43) | DAGLAABHD6DPP4 | |
| SCHEMBL7742911 | 0.76 | ABHD6 (0.43) | DAGLAABHD6DPP4 | |
| SCHEMBL10388380 | 0.75 | SLC6A4 (0.60) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1345724-A | Indolylpiperidine compound and preparation process and use thereof | SHANGHAI PHARMACEUTICAL INST C (CN) | 2002-04-24 | — | — | CN | claimed |
| JP-11171861-A | — | — | None | — | — | JP | disclosed |
| JP-H11171861-A | PRODUCTION OF DONEPEZIL | EISAI CO LTD | 1999-06-29 | — | — | JP | disclosed |