SCHEMBL11136205

SCHEMBL11136205

C=C1CC(=O)N(CCCCC)C1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 6/20 0.44
FAAH O00519 4/20 0.44
PTGS1 P23219 3/20 0.44
PTGS2 P35354 3/20 0.44
ALDH1A1 P00352 3/20 0.42
MAPT P10636 2/20 0.42
GAA P10253 1/20 0.42
THRB P10828 1/20 0.42
KDM4E B2RXH2 2/20 0.40
ALDH2 P05091 1/20 0.39
ALDH3A1 P30838 1/20 0.39
CES1 P23141 2/20 0.38
CDC25A P30304 1/20 0.38
CYP19A1 P11511 3/20 0.37
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
POLB P06746 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL410345 0.98 MGLL (0.47) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL18840672 0.98 MGLL (0.47) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL5970022 0.98 MGLL (0.47) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL406778 0.98 MGLL (0.47) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL409034 0.94 KDM4E (0.44) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL26797334 0.90 MAPT (0.41) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL13864176 0.89 MGLL (0.40) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL13864174 0.89 MGLL (0.56) MGLLFAAHPTGS1PTGS2MAPT
SCHEMBL13864166 0.88 MAPT (0.43) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL4903716 0.86 CYP19A1 (0.33) ALDH1A1MAPTGAATHRBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0034556-B1 PLANT-GROWTH REGULATING COMPOSITIONS CONTAINING AS ACTIVE AGENT 2-METHYLENE-SUCCINAMIC ACID DERIVATIVES, AND DERIVATIVES OF THIS ACID USEFUL IN THESE COMPOSITIONS RHONE-POULENC AGROCHIMIE (FR) 1984-02-01 EP disclosed
EP-0034556-A2 Plant-growth regulating compositions containing as active agent 2-methylene-succinamic acid derivatives, and derivatives of this acid useful in these compositions RHONE-POULENC AGROCHIMIE (FR) 1981-08-26 EP disclosed