SCHEMBL26797334

SCHEMBL26797334

C=C1CC(=O)N(CCCCN2C(=O)CC(=C)C2=O)C1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
RECQL P46063 2/20 0.41
USP2 O75604 2/20 0.41
KDM4E B2RXH2 1/20 0.41
POLB P06746 1/20 0.41
BLM P54132 1/20 0.41
FAAH O00519 2/20 0.36
MGLL Q99685 2/20 0.36
GAA P10253 2/20 0.35
MAPK1 P28482 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
HTT P42858 3/20 0.34
ALDH1A1 P00352 2/20 0.34
LMNA P02545 2/20 0.34
HSP90AA1 P07900 1/20 0.34
TLR9 Q9NR96 1/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13864166 0.98 MAPT (0.43) MAPTMEN1KMT2ARECQLUSP2
SCHEMBL6835923 0.91 MAPT (0.35) MAPTMEN1KMT2ARECQLUSP2
SCHEMBL11136205 0.90 MGLL (0.44) MAPTMEN1KMT2ARECQLUSP2
SCHEMBL406778 0.89 MGLL (0.47) MAPTMEN1KMT2ARECQLUSP2
SCHEMBL5970022 0.89 MGLL (0.47) MAPTMEN1KMT2ARECQLUSP2
SCHEMBL18840672 0.89 MGLL (0.47) MAPTMEN1KMT2ARECQLUSP2
SCHEMBL410345 0.89 MGLL (0.47) MAPTMEN1KMT2ARECQLUSP2
SCHEMBL409034 0.88 KDM4E (0.44) MAPTMEN1KMT2ARECQLUSP2
SCHEMBL23430477 0.83 MAPT (0.35) MAPTMEN1KMT2ARECQLUSP2
SCHEMBL4895048 0.83 MAPT (0.32) MAPTMEN1KMT2ARECQLUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365730-A1 HIGH TEMPERATURE BENZOXAZINE RESINS, METHODS, AND USES THEREOF KANEKA CORPORATION (JP) 2023-11-16 US disclosed
US-20230365730-A1 HIGH TEMPERATURE BENZOXAZINE RESINS, METHODS, AND USES THEREOF KANEKA CORPORATION (JP) 2023-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365730-A1 HIGH TEMPERATURE BENZOXAZINE RESINS, METHODS, AND USES THEREOF KDM5C, DHX15, KDM5A MAPT 969/4885MEN1 4568/4885KMT2A 511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.