Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11140033 | 0.88 | GAA (0.68) | NOX1POLBSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11420450 | 0.84 | NOX1 (0.53) | NOX1POLBSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11136324 | 0.84 | ALDH1A1 (0.59) | SMN1; SMN2MAPTALDH1A1GAANPC1 | |
| SCHEMBL11143189 | 0.84 | RAB9A (0.57) | SMN1; SMN2MAPTALDH1A1GAANPC1 | |
| SCHEMBL6929125 | 0.84 | GAA (0.70) | NOX1POLBSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10592729 | 0.84 | NOX1 (0.59) | NOX1POLBSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11056083 | 0.82 | MAPK1 (0.51) | NOX1POLBSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL11140664 | 0.82 | ALDH1A1 (0.58) | NOX1POLBSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11140703 | 0.82 | NOX1 (0.47) | NOX1POLBSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11140578 | 0.81 | IDO1 (0.66) | NOX1POLBSMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4418209-A | ANTIULCER, ANTIARRYTHMIC, ANTIDIARRHEAL, ANTISPASMODIC, ANTIPARASITIC, AND ANTISECRETORY AGENTS | WILLIAM H. RORER, INC. (US) | 1983-11-29 | — | — | US | disclosed |