Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11405358 | 0.84 | SIGMAR1 (0.54) | ALDH1A1NPSR1NPY1RNPY2RSIGMAR1 | |
| SCHEMBL11143189 | 0.84 | RAB9A (0.57) | ALDH1A1NPSR1MEN1KMT2AMAPT | |
| SCHEMBL15349132 | 0.84 | ALDH1A1 (0.59) | ALDH1A1NPSR1NPY1RNPY2RSIGMAR1 | |
| SCHEMBL9316463 | 0.84 | SIGMAR1 (0.59) | ALDH1A1NPSR1NPY1RNPY2RSIGMAR1 | |
| SCHEMBL31091544 | 0.84 | ALDH1A1 (0.59) | ALDH1A1NPSR1NPY1RNPY2RSIGMAR1 | |
| SCHEMBL31388327 | 0.84 | ALDH1A1 (0.78) | ALDH1A1NPSR1NPY1RNPY2RSIGMAR1 | |
| SCHEMBL11136359 | 0.82 | NOX1 (0.67) | ALDH1A1MAPTPOLBLMNANPC1 | |
| SCHEMBL11140703 | 0.82 | NOX1 (0.47) | ALDH1A1SIGMAR1MEN1KMT2AMAPT | |
| SCHEMBL11276279 | 0.82 | MAPT (0.55) | ALDH1A1NPSR1NPY1RNPY2RSIGMAR1 | |
| SCHEMBL11135282 | 0.80 | ALDH1A1 (0.59) | ALDH1A1NPSR1NPY1RNPY2RMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4418209-A | ANTIULCER, ANTIARRYTHMIC, ANTIDIARRHEAL, ANTISPASMODIC, ANTIPARASITIC, AND ANTISECRETORY AGENTS | WILLIAM H. RORER, INC. (US) | 1983-11-29 | — | — | US | disclosed |