Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3494668 | 0.76 | MAOA (0.41) | ALDH1A1BRD4POLB | |
| SCHEMBL18701258 | 0.69 | ALDH1A1 (0.42) | HSD17B10LMNASMN1; SMN2KMT2ACYP2C19 | |
| SCHEMBL10949854 | 0.67 | BRD4 (0.46) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL23402711 | 0.67 | MAPT (0.44) | HSD17B10LMNASMN1; SMN2KMT2ANSD3 | |
| SCHEMBL22536926 | 0.65 | BRD4 (0.44) | HSD17B10LMNASMN1; SMN2KMT2ACYP2C19 | |
| SCHEMBL1760592 | 0.65 | ESR2 (0.53) | HSD17B10LMNASMN1; SMN2KMT2ACYP2C19 | |
| SCHEMBL23402261 | 0.64 | HIF1A (0.42) | HSD17B10LMNASMN1; SMN2CYP2C19KDM4E | |
| SCHEMBL14483792 | 0.64 | ALDH1A1 (0.39) | HSD17B10LMNASMN1; SMN2KMT2ACYP2C19 | |
| SCHEMBL355552 | 0.63 | ALDH1A1 (0.55) | HSD17B10LMNASMN1; SMN2CYP2C19PDE4B | |
| SCHEMBL30335040 | 0.63 | ALOX5 (0.44) | HSD17B10LMNAKMT2ACYP2C19PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4369277-A | Pyrrole-stabilized chlorine-containing thermoplastics | CIBA-GEIGY CORPORATION (US) | 1983-01-18 | — | — | US | disclosed |