Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.51 |
| ▸ | PHGDH | O43175 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11140728 | 0.83 | NPC1 (0.62) | RAB9ANPC1CASP3SENP7ROCK2 | |
| SCHEMBL11135249 | 0.80 | ROCK2 (0.54) | RAB9ANPC1CASP3SENP7ROCK2 | |
| SCHEMBL11139118 | 0.79 | PARP1 (0.69) | RAB9ANPC1CASP3SENP7MAPT | |
| SCHEMBL10921715 | 0.78 | MAPT (0.72) | RAB9ANPC1MAPTADORA3MEN1 | |
| SCHEMBL11120333 | 0.76 | PARP1 (0.59) | RAB9ANPC1CASP3SENP7MAPT | |
| SCHEMBL10429605 | 0.76 | RAB9A (0.95) | RAB9ANPC1CASP3SENP7MAPT | |
| SCHEMBL11141502 | 0.76 | ELOVL1 (0.60) | RAB9ANPC1CASP3SENP7ROCK2 | |
| SCHEMBL11137105 | 0.76 | PARP1 (0.55) | RAB9ANPC1CASP3SENP7MAPT | |
| SCHEMBL5780078 | 0.75 | KMT2A (0.60) | RAB9ANPC1CASP3SENP7MAPT | |
| SCHEMBL11141216 | 0.75 | MEN1 (0.59) | RAB9ANPC1CASP3SENP7ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4407810-A | TREATMENT OF ALLERGIC DISORDERS | BASF AKTIENGESELLSCHAFT (DE) | 1983-10-04 | — | — | US | disclosed |
| EP-0044442-A1 | N-(4-Phenyl-2-thiazolyl)-oxamidic-acid-2-ethoxyethylester, process for its preparation and pharmaceutical compositions containing this compound | BASF Aktiengesellschaft (DE) | 1982-01-27 | — | — | EP | disclosed |