Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.56 |
| ▸ | PARP1 | P09874 | 2/20 | 0.56 |
| ▸ | PHGDH | O43175 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11120333 | 0.88 | PARP1 (0.59) | NPC1RAB9ACASP3SENP7ADORA3 | |
| SCHEMBL11141502 | 0.88 | ELOVL1 (0.60) | NPC1RAB9ACASP3SENP7ADORA3 | |
| SCHEMBL11137105 | 0.87 | PARP1 (0.55) | NPC1RAB9ACASP3SENP7ADORA3 | |
| SCHEMBL11136421 | 0.87 | POLB (0.57) | NPC1RAB9ACASP3SENP7ADORA3 | |
| SCHEMBL11139118 | 0.86 | PARP1 (0.69) | NPC1RAB9ACASP3SENP7ADORA3 | |
| SCHEMBL11143638 | 0.85 | PARP1 (0.53) | NPC1RAB9ACASP3SENP7ADORA3 | |
| SCHEMBL11141185 | 0.84 | PARP1 (0.54) | NPC1RAB9ACASP3SENP7ADORA3 | |
| SCHEMBL11139163 | 0.84 | APP (0.61) | NPC1RAB9ACASP3SENP7ADORA3 | |
| SCHEMBL11137133 | 0.83 | RAB9A (0.58) | NPC1RAB9ACASP3SENP7ADORA3 | |
| SCHEMBL11135249 | 0.81 | ROCK2 (0.54) | NPC1RAB9ACASP3SENP7ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4407810-A | TREATMENT OF ALLERGIC DISORDERS | BASF AKTIENGESELLSCHAFT (DE) | 1983-10-04 | — | — | US | claimed |
| US-4407810-A | TREATMENT OF ALLERGIC DISORDERS | BASF AKTIENGESELLSCHAFT (DE) | 1983-10-04 | — | — | US | disclosed |