SCHEMBL385227

SCHEMBL385227

O=C(OC=Cc1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 2/20 0.53
LMNA P02545 4/20 0.52
MAPT P10636 4/20 0.52
PLIN1 O60240 2/20 0.52
RECQL P46063 2/20 0.52
PLIN5 Q00G26 2/20 0.52
ABHD5 Q8WTS1 2/20 0.52
MAOB P27338 2/20 0.52
CYP1B1 Q16678 2/20 0.52
BCHE P06276 1/20 0.52
TNFRSF1A P19438 1/20 0.52
ACHE P22303 1/20 0.52
F2 P00734 1/20 0.50
RAB9A P51151 3/20 0.47
NPC1 O15118 2/20 0.47
HDAC1 Q13547 3/20 0.47
TSHR P16473 2/20 0.47
HDAC3 O15379 2/20 0.47
HDAC4 P56524 2/20 0.47
HDAC2 Q92769 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10455847 1.00 PLA2G7 (0.53) PLA2G7LMNAMAPTPLIN1RECQL
SCHEMBL3871441 0.96 PLA2G7 (0.49) PLA2G7LMNAMAPTPLIN1RECQL
SCHEMBL3871440 0.96 PLA2G7 (0.49) PLA2G7LMNAMAPTPLIN1RECQL
SCHEMBL28305859 0.91 MAOB (0.47) PLA2G7LMNAMAPTPLIN1RECQL
SCHEMBL27494117 0.91 KMT2A (0.46) PLA2G7LMNAMAPTPLIN1RECQL
SCHEMBL27558525 0.88 CYP1B1 (0.58) PLA2G7LMNAMAPTPLIN1RECQL
SCHEMBL27567956 0.88 L3MBTL1 (0.47) PLA2G7LMNACYP1B1F2RAB9A
SCHEMBL17066806 0.88 PLA2G7 (0.56) PLA2G7LMNAMAOBTNFRSF1AF2
SCHEMBL21063574 0.88 NPC1 (0.50) PLA2G7MAPTCYP1B1RAB9ANPC1
SCHEMBL11138151 0.86 TTR (0.55) PLA2G7BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119899305-A Polypeptide solid-phase synthesis carrier and preparation method thereof 西安蓝晓科技新材料股份有限公司 2025-04-29 CN claimed
CN-118271496-A Isoalkenyl terpolymer containing oxygen polar groups and preparation method thereof 常州汉韦聚合物有限公司 2024-07-02 CN claimed
US-20240010774-A1 SOLID-PHASE SYNTHESIS CARRIER, PREPARATION METHOD THEREFOR AND USE THEREOF SUNRESIN NEW MATERIALS CO. LTD. (CN) 2024-01-11 US claimed
US-20230312859-A1 POROUS RESIN USED TO SOLID PHASE SYNTHESSIS AND PREPARATION METHOD THEREFOR SUNRESIN NEW MATERIALS CO. LTD. (CN) 2023-10-05 US claimed
CN-114539458-B Porous resin applied to solid phase synthesis and preparation method thereof 西安蓝晓科技新材料股份有限公司 2023-07-25 CN claimed
CN-114539459-B Solid phase synthesis carrier and preparation method and application thereof 西安蓝晓科技新材料股份有限公司 2023-07-25 CN claimed
EP-4190825-A1 SOLID-PHASE SYNTHESIS CARRIER, PREPARATION METHOD THEREFOR AND USE THEREOF Sunresin New Materials Co. Ltd., Xi'an (CN) 2023-06-07 EP claimed
EP-4177281-A1 POROUS RESIN USED TO SOLID PHASE SYNTHESIS AND PREPARATION METHOD THEREFOR Sunresin New Materials Co. Ltd., Xi'an (CN) 2023-05-10 EP claimed
WO-2022110559-A1 SOLID-PHASE SYNTHESIS CARRIER, PREPARATION METHOD THEREFOR AND USE THEREOF 西安蓝晓科技新材料股份有限公司 2022-06-02 WO claimed
WO-2022110560-A1 POROUS RESIN USED TO SOLID PHASE SYNTHESIS AND PREPARATION METHOD THEREFOR 西安蓝晓科技新材料股份有限公司 2022-06-02 WO claimed
CN-114539459-A Solid-phase synthesis carrier and preparation method and application thereof 西安蓝晓科技新材料股份有限公司 2022-05-27 CN claimed
CN-114539458-A Porous resin applied to solid phase synthesis and preparation method thereof 西安蓝晓科技新材料股份有限公司 2022-05-27 CN claimed
CN-108653299-A A kind of preparation method of dialyzate 北京点域科技有限公司 2018-10-16 CN claimed
US-8101700-B2 Phosphonic polymers having a phosphinate backbone and methods of making and using thereof UNICHEM TECHNOLOGIES, INC. (US) 2012-01-24 US claimed
US-20100168361-A1 PHOSPHONIC POLYMERS HAVING A PHOSPHINATE BACKBONE AND METHODS OF MAKING AND USING THEREOF UNICHEM TECHNOLOGIES, INC. (US) 2010-07-01 US claimed
US-20090005527-A1 PHOSPHONIC COMPOUNDS AND METHODS OF USE THEREOF SUNTRUST BANK 2009-01-01 US claimed
US-5071953-A Dissolving in solvent, applying to substrate, desolventizing by evaporation IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-12-10 US claimed
US-4137137-A Radiation process for the production of graft copolymer to be used for ion-exchange membrane JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1979-01-30 US claimed
CN-115947761-B Ruthenium carbene catalyst, composition containing ruthenium carbene catalyst, preparation method and application of ruthenium carbene catalyst 上海中化科技有限公司 2026-05-15 CN disclosed
US-4069169-A TITANIUM TETRAHALIDE, BENZOIC ACID ESTER DERIVATIVES MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1978-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090005527-A1 PHOSPHONIC COMPOUNDS AND METHODS OF USE THEREOF PHOSPHO1, PPIP5K2, FASN PLA2G7 309/4885LMNA 1294/4885MAPT 2417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.