Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | HAAO | P46952 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1505827 | 0.89 | TDP1 (0.61) | TDP1MAPTALDH1A1HSD17B10POLB | |
| Hydrochloric Acid SCHEMBL2202243 | 0.87 | TDP1 (0.59) | TDP1MAPTALDH1A1HSD17B10POLB | |
| SCHEMBL4638173 | 0.82 | MAPT (0.55) | TDP1MAPTALDH1A1CYP1A2MAPK1 | |
| SCHEMBL6646160 | 0.79 | TDP1 (0.52) | TDP1MAPTALDH1A1HSD17B10POLB | |
| SCHEMBL419245 | 0.79 | TDP1 (0.56) | TDP1MAPTALDH1A1HSD17B10POLB | |
| SCHEMBL102827 | 0.79 | MAPT (0.72) | TDP1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL6852883 | 0.79 | MAPT (0.52) | TDP1MAPTALDH1A1HSD17B10POLB | |
| SCHEMBL9679999 | 0.78 | TDP1 (0.55) | TDP1MAPTALDH1A1HSD17B10POLB | |
| SCHEMBL14699894 | 0.78 | ALDH1A1 (0.63) | TDP1MAPTALDH1A1HSD17B10POLB | |
| SCHEMBL11046315 | 0.78 | MAPT (0.50) | TDP1MAPTALDH1A1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4376825-A | ENZYME-BOUND LIGANDS WITH FREE REACTIVE SITES WHICH CAN BIND RECEPTORS | SYVA COMPANY (US) | 1983-03-15 | — | — | US | disclosed |
| US-4282325-A | FOR AMPLIFICATION IN ASSAYS | SYVA COMPANY (US) | 1981-08-04 | — | — | US | disclosed |
| US-4203802-A | ENZYME BOUND TO AN ESTROGEN LIGAND | SYVA COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4190496-A | RECEPTOR, LIGAND, AND ENZYME-BOUND | SYVA COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4067774-A | Compounds for enzyme amplification assay | SYVA COMPANY (US) | 1978-01-10 | — | — | US | disclosed |
| US-3975237-A | LIGANDS | SYVA COMPANY (US) | 1976-08-17 | — | — | US | disclosed |
| US-3966764-A | ELECTRON SPIN RESONANCE | SYVA COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
| US-3966556-A | Compounds for enzyme amplification assay methadone analogs | SYVA COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
| US-3966744-A | Spin labeled compounds | SYVA COMPANY (US) | 1976-06-29 | — | — | US | disclosed |