Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1505827 | 0.88 | TDP1 (0.61) | TDP1MAPTALDH1A1HSD17B10POLB | |
| Hydrochloric Acid SCHEMBL2202243 | 0.86 | TDP1 (0.59) | TDP1MAPTALDH1A1HSD17B10POLB | |
| SCHEMBL8967035 | 0.86 | CDC25B (0.56) | TDP1MAPTALDH1A1HSD17B10POLB | |
| SCHEMBL1671110 | 0.81 | CYP1A1 (0.64) | TDP1MAPTALDH1A1KDM4ECDC25B | |
| SCHEMBL23724854 | 0.80 | POLB (0.54) | TDP1MAPTALDH1A1HSD17B10POLB | |
| SCHEMBL4138140 | 0.80 | ESR1 (0.49) | TDP1MAPTALDH1A1HSD17B10POLB | |
| SCHEMBL39857 | 0.79 | ALDH1A1 (0.55) | TDP1MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL419245 | 0.78 | TDP1 (0.56) | TDP1MAPTALDH1A1HSD17B10POLB | |
| SCHEMBL102827 | 0.78 | MAPT (0.72) | TDP1MAPTALDH1A1KDM4ECDC25B | |
| SCHEMBL18529850 | 0.78 | TDP1 (0.52) | TDP1MAPTALDH1A1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5097015-A | Fibers, filaments, films and sheets | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |