Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.58 |
| ▸ | PYGL | P06737 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.47 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.47 |
| ▸ | PNLIP | P16233 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11143585 | 0.90 | NPC1 (0.52) | GCGRPYGLNPC1RAB9ATDP1 | |
| SCHEMBL11141988 | 0.87 | GCGR (0.60) | GCGRPYGLNPC1RAB9APOLB | |
| SCHEMBL11138807 | 0.86 | GCGR (0.62) | GCGRPYGLNPC1RAB9APOLB | |
| Chlorbenzuron SCHEMBL5177776 | 0.81 | GCGR (0.68) | GCGRPYGLNPC1RAB9APOLB | |
| SCHEMBL11240787 | 0.81 | GCGR (0.53) | GCGRPYGLNPC1RAB9APOLB | |
| SCHEMBL11036755 | 0.80 | RAB9A (0.60) | GCGRPYGLNPC1RAB9APOLB | |
| SCHEMBL8840342 | 0.80 | NPC1 (0.60) | GCGRPYGLNPC1RAB9APOLB | |
| SCHEMBL11240601 | 0.79 | PYGL (0.42) | GCGRPYGLNPC1RAB9APOLB | |
| SCHEMBL10617761 | 0.79 | NPC1 (0.59) | GCGRPYGLNPC1RAB9APOLB | |
| SCHEMBL8840248 | 0.79 | RAB9A (0.59) | GCGRPYGLNPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4399152-A | Substituted benzoyl ureas as insecticides | DUPHAR INTERNATIONAL B.V. (NL) | 1983-08-16 | — | — | US | disclosed |