Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 9/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | TYK2 | P29597 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11140802 | 0.79 | GCGR (0.58) | PYGLGCGRCYP1A2POLBNPC1 | |
| SCHEMBL11143585 | 0.74 | NPC1 (0.52) | PYGLGCGRNPC1RAB9AMEN1 | |
| SCHEMBL11251201 | 0.72 | TDP1 (0.47) | PYGLGCGRJAK2TYK2CYP1A2 | |
| SCHEMBL28072777 | 0.72 | JAK2 (0.67) | CYP11B2JAK2TYK2CYP3A4HTT | |
| SCHEMBL8658810 | 0.69 | PYGL (0.45) | PYGLGCGRCYP1A2POLBNPC1 | |
| SCHEMBL8840342 | 0.69 | NPC1 (0.60) | PYGLGCGRJAK2TYK2CYP1A2 | |
| SCHEMBL11234133 | 0.68 | NPC1 (0.51) | PYGLGCGRCYP1A2POLBNPC1 | |
| SCHEMBL8840248 | 0.68 | RAB9A (0.59) | PYGLGCGRCYP1A2POLBNPC1 | |
| SCHEMBL10617761 | 0.68 | NPC1 (0.59) | PYGLGCGRCYP1A2POLBNPC1 | |
| SCHEMBL8840275 | 0.67 | POLB (0.57) | PYGLGCGRJAK2TYK2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |