Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1114157 | 0.88 | PABPC1 (0.42) | PABPC1EIF4HCTDSP1KMT2ASMN1; SMN2 | |
| SCHEMBL1114158 | 0.85 | PABPC1 (0.39) | PABPC1EIF4HCTDSP1KMT2ASMN1; SMN2 | |
| SCHEMBL8159898 | 0.81 | PABPC1 (0.41) | PABPC1EIF4HCTDSP1SMN1; SMN2LMNA | |
| Tetrabuthylammonium SCHEMBL1113137 | 0.81 | SMN1; SMN2 (0.39) | PABPC1EIF4HCTDSP1SMN1; SMN2RXFP1 | |
| SCHEMBL15345877 | 0.77 | PABPC1 (0.34) | PABPC1EIF4HCTDSP1CHRM2ADRA2A | |
| SCHEMBL1114160 | 0.76 | MAPT (0.43) | PABPC1EIF4HCTDSP1KMT2ASMN1; SMN2 | |
| SCHEMBL8153475 | 0.76 | PABPC1 (0.41) | PABPC1EIF4HCTDSP1SMN1; SMN2LMNA | |
| SCHEMBL30496790 | 0.76 | ACHE (0.49) | PABPC1EIF4HCTDSP1CHRM2ADRA2A | |
| SCHEMBL1111715 | 0.75 | CHRM2 (0.45) | PABPC1EIF4HCTDSP1CHRM2ADRA2A | |
| SCHEMBL1114103 | 0.75 | SMN1; SMN2 (0.39) | CTDSP1CHRM2CHRM1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279192-B1 | IONIC LIQUIDS | MERCK PATENT GMBH (DE) | 2013-10-30 | — | — | EP | claimed |
| US-8642778-B2 | Ionic liquids | MERCK PATENT GMBH (DE) | 2014-02-04 | — | — | US | disclosed |
| EP-2279192-B1 | IONIC LIQUIDS | MERCK PATENT GMBH (DE) | 2013-10-30 | — | — | EP | disclosed |
| US-20110152537-A1 | IONIC LIQUIDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-06-23 | — | — | US | disclosed |
| EP-2279192-A2 | IONIC LIQUIDS | Merck Patent GmbH (DE) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009152902-A2 | IONIC LIQUIDS | MERCK PATENT GMBH, (DE) | 2009-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152537-A1 | IONIC LIQUIDS | HCN3, CHRNA3, CHRM3 | PABPC1 4560/4885EIF4H 4418/4885CTDSP1 2321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.