Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11137457 | 0.97 | ALDH1A1 (0.49) | ALDH1A1CYP2C19SMN1; SMN2EPHX2KMT2A | |
| SCHEMBL11143476 | 0.95 | ALDH1A1 (0.47) | ALDH1A1EPHX2KMT2A | |
| SCHEMBL11142321 | 0.86 | CARM1 (0.58) | CYP2C19SMN1; SMN2KMT2ALMNA | |
| SCHEMBL11148320 | 0.86 | ADIPOR2 (0.47) | ALDH1A1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL11255924 | 0.85 | ADIPOR2 (0.46) | ALDH1A1DRD2DRD3 | |
| SCHEMBL11141846 | 0.84 | ADIPOR2 (0.50) | ALDH1A1CYP2C19SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL11144955 | 0.84 | ADIPOR2 (0.45) | ALDH1A1DRD2DRD3 | |
| SCHEMBL11142195 | 0.82 | KMT2A (0.44) | ALDH1A1CYP2C19SMN1; SMN2EPHX2KMT2A | |
| SCHEMBL11144343 | 0.82 | ADIPOR2 (0.48) | ALDH1A1CYP2C19SMN1; SMN2KMT2ADRD2 | |
| SCHEMBL11142374 | 0.81 | ADIPOR2 (0.48) | ALDH1A1CYP2C19SMN1; SMN2KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339576-A | Anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory 1-[(benzoylphenyl)-lower-alkyl]piperidines and analogs thereof | STERLING DRUG INC. (US) | 1982-07-13 | — | — | US | claimed |
| EP-0052311-A1 | 1-((Benzoylphenyl) - lower-alkyl) piperidines and carbinol analogs and preparation thereof | STERLING DRUG INC. (US) | 1982-05-26 | — | — | EP | claimed |
| US-4396765-A | ANTIASTHMATICS, BRONCHODILATORS | STERLING DRUG INC. (US) | 1983-08-02 | — | — | US | disclosed |
| US-4339576-A | Anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory 1-[(benzoylphenyl)-lower-alkyl]piperidines and analogs thereof | STERLING DRUG INC. (US) | 1982-07-13 | — | — | US | disclosed |
| EP-0052311-A1 | 1-((Benzoylphenyl) - lower-alkyl) piperidines and carbinol analogs and preparation thereof | STERLING DRUG INC. (US) | 1982-05-26 | — | — | EP | disclosed |