Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADIPOR2 | Q86V24 | 1/20 | 0.48 |
| ▸ | ADIPOR1 | Q96A54 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11141846 | 0.88 | ADIPOR2 (0.50) | ADIPOR2ADIPOR1CYP3A4HPGDCYP2C19 | |
| SCHEMBL11144343 | 0.86 | ADIPOR2 (0.48) | ADIPOR2ADIPOR1CYP3A4HPGDCYP2C19 | |
| SCHEMBL11148320 | 0.86 | ADIPOR2 (0.47) | ADIPOR2ADIPOR1DRD2DRD3ALDH1A1 | |
| SCHEMBL11142321 | 0.86 | CARM1 (0.58) | CYP3A4CYP2C19MEN1KMT2ASCN1A | |
| Hydrochloric Acid SCHEMBL11255924 | 0.85 | ADIPOR2 (0.46) | ADIPOR2ADIPOR1DRD2DRD3ALDH1A1 | |
| SCHEMBL11142378 | 0.84 | SSTR4 (0.43) | ADIPOR2ADIPOR1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11144955 | 0.84 | ADIPOR2 (0.45) | ADIPOR2ADIPOR1DRD2DRD3ALDH1A1 | |
| SCHEMBL11143476 | 0.84 | ALDH1A1 (0.47) | ADIPOR2ADIPOR1HPGDKMT2AALDH1A1 | |
| SCHEMBL11137457 | 0.82 | ALDH1A1 (0.49) | HPGDCYP2C19KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11142186 | 0.81 | ALDH1A1 (0.53) | CYP2C19DRD2DRD3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339576-A | Anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory 1-[(benzoylphenyl)-lower-alkyl]piperidines and analogs thereof | STERLING DRUG INC. (US) | 1982-07-13 | — | — | US | claimed |
| US-4396765-A | ANTIASTHMATICS, BRONCHODILATORS | STERLING DRUG INC. (US) | 1983-08-02 | — | — | US | disclosed |
| US-4339576-A | Anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory 1-[(benzoylphenyl)-lower-alkyl]piperidines and analogs thereof | STERLING DRUG INC. (US) | 1982-07-13 | — | — | US | disclosed |
| US-4304911-A | ANTIHISTAMINES, ANTIALLERGENS, ANTICHOLINERGIC AGENTS, ANTIINFLAMMATORY AGENTS, BRONCHODILATOR AGENTS, AND ANALGESICS | STERLING DRUG INC. (US) | 1981-12-08 | — | — | US | disclosed |