Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136396 | 0.92 | SMN1; SMN2 (0.61) | RAB9ALMNAMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL11120333 | 0.88 | PARP1 (0.59) | RAB9APOLBKMT2ANPC1MEN1 | |
| SCHEMBL11136414 | 0.86 | MAPT (0.46) | RAB9APOLBLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL11133595 | 0.83 | RAB9A (0.64) | RAB9APOLBLMNAMAPK1ALOX5 | |
| Tioxamast SCHEMBL2111615 | 0.81 | LMNA (0.67) | RAB9ALMNAMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL11143638 | 0.81 | PARP1 (0.53) | RAB9APOLBKMT2ANPC1MAPT | |
| SCHEMBL11137105 | 0.81 | PARP1 (0.55) | RAB9APOLBMAPK1KMT2ANPC1 | |
| SCHEMBL11136421 | 0.80 | POLB (0.57) | RAB9APOLBLMNAMAPK1NPC1 | |
| SCHEMBL10519957 | 0.79 | PARP1 (0.49) | RAB9APOLBLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL11144373 | 0.79 | KMT2A (0.61) | LMNAMAPK1SMN1; SMN2KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4407810-A | TREATMENT OF ALLERGIC DISORDERS | BASF AKTIENGESELLSCHAFT (DE) | 1983-10-04 | — | — | US | disclosed |
| EP-0044442-A1 | N-(4-Phenyl-2-thiazolyl)-oxamidic-acid-2-ethoxyethylester, process for its preparation and pharmaceutical compositions containing this compound | BASF Aktiengesellschaft (DE) | 1982-01-27 | — | — | EP | disclosed |