Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11137105 | 0.94 | PARP1 (0.55) | PARP1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL11120333 | 0.90 | PARP1 (0.59) | PARP1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL11140728 | 0.85 | NPC1 (0.62) | PARP1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL11139118 | 0.84 | PARP1 (0.69) | PARP1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL11141502 | 0.83 | ELOVL1 (0.60) | PARP1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL11136421 | 0.82 | POLB (0.57) | PARP1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL11141185 | 0.82 | PARP1 (0.54) | PARP1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL10519957 | 0.81 | PARP1 (0.49) | PARP1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL11136396 | 0.81 | SMN1; SMN2 (0.61) | RAB9ANPC1MAPTADORA3ALDH1A1 | |
| SCHEMBL11142941 | 0.81 | RAB9A (0.57) | PARP1RAB9ANPC1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4407810-A | TREATMENT OF ALLERGIC DISORDERS | BASF AKTIENGESELLSCHAFT (DE) | 1983-10-04 | — | — | US | disclosed |
| EP-0044442-A1 | N-(4-Phenyl-2-thiazolyl)-oxamidic-acid-2-ethoxyethylester, process for its preparation and pharmaceutical compositions containing this compound | BASF Aktiengesellschaft (DE) | 1982-01-27 | — | — | EP | disclosed |