Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | CETP | P11597 | 4/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1114555 | 0.78 | NAAA (0.35) | — | |
| SCHEMBL1114291 | 0.78 | CETP (0.35) | HCRTR1HCRTR2CETPP2RX7DAO | |
| SCHEMBL1114833 | 0.70 | HSD17B13 (0.38) | P2RX7HSD17B13 | |
| SCHEMBL1114292 | 0.69 | MEP1B (0.36) | HCRTR1HCRTR2CETPP2RX7DAO | |
| SCHEMBL1114303 | 0.69 | MEP1B (0.36) | HCRTR1HCRTR2CETPP2RX7DAO | |
| SCHEMBL1114748 | 0.67 | HSD17B13 (0.40) | HCRTR1HCRTR2CETPP2RX7HSD17B13 | |
| SCHEMBL4504413 | 0.62 | FEN1 (0.39) | HCRTR1HCRTR2CETPHSD17B13 | |
| SCHEMBL10913301 | 0.62 | MEP1B (0.50) | HCRTR1HCRTR2DAOKMT2AMEP1B | |
| SCHEMBL1776057 | 0.62 | MEP1B (0.54) | DAOKMT2AMEP1BALKBH1KCNJ5 | |
| SCHEMBL1908557 | 0.62 | MEP1B (0.50) | HCRTR1HCRTR2CETPDAOMEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2278879-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES | Institute for OneWorld Health (US) | 2011-02-02 | — | — | EP | disclosed |