Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 3/20 | 0.33 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11142403 | 0.84 | ALDH1A3 (0.43) | ALDH1A1ALDH1A3MAPTKMT2AALDH3A1 | |
| SCHEMBL11143387 | 0.81 | ALDH1A1 (0.42) | ALDH1A1ALDH1A3MAPTKMT2AALDH3A1 | |
| SCHEMBL11135728 | 0.76 | SCN9A (0.49) | ALDH1A1ALDH1A3KMT2AALDH3A1HSD17B10 | |
| SCHEMBL9092776 | 0.76 | KMT2A (0.50) | ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL1418463 | 0.76 | ALDH1A1 (0.53) | ALDH1A1ALDH1A3MAPTKMT2AALDH3A1 | |
| SCHEMBL30186040 | 0.76 | ALDH1A1 (0.53) | ALDH1A1ALDH1A3MAPTKMT2AALDH3A1 | |
| SCHEMBL11149870 | 0.75 | ALDH1A1 (0.36) | ALDH1A1ALDH1A3MAPTKMT2AALDH3A1 | |
| SCHEMBL12432981 | 0.75 | ALDH1A3 (0.41) | ALDH1A1ALDH1A3MAPTKMT2AALDH3A1 | |
| SCHEMBL2315289 | 0.74 | NOS3 (0.44) | ALDH1A1ALDH1A3MAPTKMT2AALDH3A1 | |
| SCHEMBL2315889 | 0.74 | ALDH1A3 (0.43) | ALDH1A1ALDH1A3MAPTKMT2AALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4403095-A | DYEING POLYACRYLONITRILES | CIBA-GEIGY CORPORATION (US) | 1983-09-06 | — | — | US | disclosed |