Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30186040 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL7353819 | 0.90 | ALDH1A1 (0.51) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL21872800 | 0.84 | CYP11B1 (0.48) | ALDH1A1MAPTNOTUMCYP11B1CYP11B2 | |
| SCHEMBL14744979 | 0.81 | MYC (0.50) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| SCHEMBL14744980 | 0.81 | MYC (0.50) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| SCHEMBL16440970 | 0.81 | MYC (0.50) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| SCHEMBL6177816 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL11143387 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL11142403 | 0.78 | ALDH1A3 (0.43) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL9141312 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MEN1GAAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4580750-A1 | SORTILIN MODULATORS | Vesper Bio Aps (DK) | 2025-07-09 | — | — | EP | disclosed |
| US-11958837-B2 | Quinazolinones as PARP14 inhibitors | RIBON THERAPEUTICS, INC. (US) | 2024-04-16 | — | — | US | disclosed |
| EP-4342530-A1 | SORTILIN MODULATORS | Insusense ApS (DK) | 2024-03-27 | — | — | EP | disclosed |
| WO-2024047227-A1 | SORTILIN MODULATORS | INSUSENSE ApS (DK) | 2024-03-07 | — | — | WO | disclosed |
| EP-4212515-A1 | QUINAZOLINONES AS PARP14 INHIBITORS | Ribon Therapeutics Inc. (US) | 2023-07-19 | — | — | EP | disclosed |
| EP-3405477-B1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |
| US-20230141569-A1 | FLUORESCENT DYE, AND PREPARATION METHOD AND USES THEREOF | FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY LTD. (CN) | 2023-05-11 | — | — | US | disclosed |
| US-20230141569-A1 | FLUORESCENT DYE, AND PREPARATION METHOD AND USES THEREOF | FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY LTD. (CN) | 2023-05-11 | — | — | US | disclosed |
| US-11603349-B2 | Anti-fibrotic compounds | CERTA THERAPEUTICS PTY LTD (AU) | 2023-03-14 | — | — | US | disclosed |
| WO-2023011657-A1 | METHOD FOR DETECTING AND QUANTIFYING RNA | 纳莹(上海)生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |
| US-6143746-A | Combination of tadalafil and another drug for cGMP-specific PDE inhibition; erectile dysfunction, cardiovascular disorders | ICOS CORPORATION (US) | 2000-11-07 | — | — | US | disclosed |
| US-6127542-A | CHEMICAL INTERMEDIATES TO SPECIFIED PYRAZINO(2',1':6,1)PYRIDO(3,4B)INDOLE-1,4-DIONES WHICH ARE SELECTIVE INHIBITORS OF CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE SPECIFIC PHOSPHODIESTERASE; TO TREAT CARDIOVASCULAR DISORDERS | ICOS CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| US-6025494-A | CYCLIZATION OF DICARBONYL-SUBSTITUTED PYRIDOINDOLES YIELDS PHOSPHODIESTERASE INHIBITORS | ICOS CORPORATION (US) | 2000-02-15 | — | — | US | disclosed |
| US-5859006-A | CYCLIZATION; AMIDATION; SELECTIVE INHIBITOR OF CYCLIC GUANOSINE 3',5'-MONOPHOSPHATASE SPECIFIC PHOSPHODIESTERASE; USEFUL IN THE TREATMENT OF CARDIOVASCULAR DISORDERS; TADALAFIL CLAIMED | ICOS CORPORATION (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0740668-B1 | TETRACYCLIC DERIVATIVES, PROCESS OF PREPARATION AND USE | ICOS CORP (US) | 1998-07-29 | — | — | EP | disclosed |
| EP-0740668-A1 | TETRACYCLIC DERIVATIVES, PROCESS OF PREPARATION AND USE | LABORATORIES GLAXO WELLCOME S.A. (FR) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995019978-A1 | TETRACYCLIC DERIVATIVES, PROCESS OF PREPARATION AND USE | LABORATOIRES GLAXO WELLCOME S.A. (FR) | 1995-07-27 | — | — | WO | disclosed |
| EP-0037374-B1 | METHINIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1983-12-28 | — | — | EP | disclosed |
| US-4403095-A | DYEING POLYACRYLONITRILES | CIBA-GEIGY CORPORATION (US) | 1983-09-06 | — | — | US | disclosed |
| EP-0037374-A2 | Methinic compounds | CIBA-GEIGY AG (CH) | 1981-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11958837-B2 | Quinazolinones as PARP14 inhibitors | PARP14, PARP15, PARP11 | ALDH1A1 2388/4885MEN1 2734/4885GAA 3263/4885 |
| US-11603349-B2 | Anti-fibrotic compounds | TGFB1, SMAD3, TGFB2 | ALDH1A1 1274/4885MEN1 3362/4885GAA 1453/4885 |
| US-20230141569-A1 | FLUORESCENT DYE, AND PREPARATION METHOD AND USES THEREOF | DNASE1, DNA2, RNGTT | ALDH1A1 599/4885MEN1 3900/4885GAA 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.