Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.62 |
| ▸ | DRD4 | P21917 | 4/20 | 0.58 |
| ▸ | LTA4H | P09960 | 3/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | ADIPOR2 | Q86V24 | 1/20 | 0.51 |
| ▸ | ADIPOR1 | Q96A54 | 1/20 | 0.51 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8023030 | 0.90 | SIGMAR1 (0.75) | SIGMAR1DRD4LTA4HKCNH2HTR2A | |
| Phenol SCHEMBL10513506 | 0.85 | SIGMAR1 (0.68) | SIGMAR1DRD4LTA4HKCNH2HTR2A | |
| SCHEMBL11297108 | 0.82 | DRD4 (0.64) | SIGMAR1DRD4LTA4HKCNH2CXCR3 | |
| SCHEMBL17512174 | 0.81 | DRD4 (0.76) | SIGMAR1DRD4KCNH2HTR2ACARM1 | |
| SCHEMBL9871216 | 0.80 | LTA4H (0.60) | SIGMAR1LTA4HKCNH2 | |
| Hydrochloric Acid SCHEMBL11146240 | 0.80 | HTR2A (0.59) | SIGMAR1KCNH2HTR2AADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL11299920 | 0.80 | HTR2A (0.59) | SIGMAR1KCNH2HTR2AADRA1AADRA1B | |
| SCHEMBL27430491 | 0.79 | SIGMAR1 (0.79) | SIGMAR1DRD4HTR2ACXCR3 | |
| SCHEMBL11148320 | 0.79 | ADIPOR2 (0.47) | LTA4HCARM1PRMT6DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL11255924 | 0.78 | ADIPOR2 (0.46) | LTA4HCARM1PRMT6DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339576-A | Anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory 1-[(benzoylphenyl)-lower-alkyl]piperidines and analogs thereof | STERLING DRUG INC. (US) | 1982-07-13 | — | — | US | claimed |
| US-4396765-A | ANTIASTHMATICS, BRONCHODILATORS | STERLING DRUG INC. (US) | 1983-08-02 | — | — | US | disclosed |
| US-4339576-A | Anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory 1-[(benzoylphenyl)-lower-alkyl]piperidines and analogs thereof | STERLING DRUG INC. (US) | 1982-07-13 | — | — | US | disclosed |
| EP-0052311-A1 | 1-((Benzoylphenyl) - lower-alkyl) piperidines and carbinol analogs and preparation thereof | STERLING DRUG INC. (US) | 1982-05-26 | — | — | EP | disclosed |
| US-4304911-A | ANTIHISTAMINES, ANTIALLERGENS, ANTICHOLINERGIC AGENTS, ANTIINFLAMMATORY AGENTS, BRONCHODILATOR AGENTS, AND ANALGESICS | STERLING DRUG INC. (US) | 1981-12-08 | — | — | US | disclosed |