Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12644446 | 0.69 | TAAR1 (0.56) | KDM4EALDH1A1GAALMNAMAPT | |
| SCHEMBL1114402 | 0.67 | ALDH1A1 (0.41) | TEAD1KDM4EALDH1A1GAAPOLB | |
| SCHEMBL3237564 | 0.61 | TAAR1 (0.64) | KDM4EALDH1A1GAALMNAMAPT | |
| SCHEMBL9820666 | 0.60 | MEN1 (0.55) | ALDH1A1GAALMNAMAPTSMN1; SMN2 | |
| SCHEMBL13731334 | 0.60 | HTR2C (0.47) | ACP3 | |
| SCHEMBL2917906 | 0.60 | KDM4E (0.63) | TEAD1KDM4EALDH1A1GAALMNA | |
| SCHEMBL24214370 | 0.60 | ALDH1A1 (0.55) | KDM4EALDH1A1GAAPOLBLMNA | |
| SCHEMBL30376503 | 0.60 | ALDH1A1 (0.55) | KDM4EALDH1A1GAAPOLBLMNA | |
| SCHEMBL46757 | 0.60 | HTR2A (0.63) | KDM4EALDH1A1GAALMNAMAPT | |
| SCHEMBL30370404 | 0.60 | TAAR1 (0.53) | KDM4EALDH1A1GAAACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2278879-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES | Institute for OneWorld Health (US) | 2011-02-02 | — | — | EP | claimed |
| WO-2009131957-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2009-10-29 | — | — | WO | claimed |
| EP-2278879-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES | Institute for OneWorld Health (US) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009131957-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2009-10-29 | — | — | WO | disclosed |