Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1114522 | 0.87 | ALDH1A1 (0.41) | ALDH1A1KDM4EGAAFAAHPOLB | |
| SCHEMBL12644446 | 0.69 | TAAR1 (0.56) | ALDH1A1KDM4EGAALMNAHTT | |
| SCHEMBL1114403 | 0.67 | TEAD1 (0.38) | ALDH1A1KDM4EGAAFAAHPOLB | |
| SCHEMBL1114224 | 0.63 | KDM4E (0.41) | ALDH1A1KDM4EGAAPOLBLMNA | |
| SCHEMBL30424935 | 0.62 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAAPOLBLMNA | |
| SCHEMBL30747663 | 0.61 | FAAH (0.67) | ALDH1A1KDM4EGAAFAAHLMNA | |
| SCHEMBL9820666 | 0.60 | MEN1 (0.55) | ALDH1A1GAALMNAHTTMEN1 | |
| SCHEMBL4244138 | 0.60 | ALDH1A1 (0.97) | ALDH1A1KDM4EGAAFAAHPOLB | |
| SCHEMBL4240373 | 0.60 | ALDH1A1 (0.72) | ALDH1A1KDM4EGAAFAAHLMNA | |
| SCHEMBL2093612 | 0.60 | KDM4E (0.72) | ALDH1A1KDM4EGAAFAAHPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2278879-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES | Institute for OneWorld Health (US) | 2011-02-02 | — | — | EP | claimed |
| WO-2009131957-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2009-10-29 | — | — | WO | claimed |
| EP-2278879-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES | Institute for OneWorld Health (US) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009131957-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2009-10-29 | — | — | WO | disclosed |