Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1114128 | 0.84 | SCN10A (0.61) | S1PR1SCN10ASCN9ASMN1; SMN2MAPT | |
| SCHEMBL29959444 | 0.79 | TP53 (0.54) | GRM5NPC1RAB9ATP53GAA | |
| SCHEMBL60580 | 0.78 | GRM5 (0.63) | S1PR1GRM5NPC1RAB9ACSNK2A2 | |
| SCHEMBL16481833 | 0.78 | L3MBTL1 (0.64) | S1PR1GRM5XDHNPC1RAB9A | |
| SCHEMBL12377818 | 0.76 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL3722117 | 0.76 | DYRK1A (0.62) | DYRK1AXDHMAPT | |
| SCHEMBL30230560 | 0.75 | DYRK1A (0.48) | SCN10ADYRK1AXDHSCN9AMAPT | |
| SCHEMBL16088930 | 0.75 | S1PR1 (0.54) | S1PR1GRM5SCN10AXDHNPC1 | |
| SCHEMBL31323246 | 0.75 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL28243415 | 0.73 | NR1H4 (0.66) | S1PR1GRM5NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2278879-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES | Institute for OneWorld Health (US) | 2011-02-02 | — | — | EP | disclosed |