Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1681681 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CHRNA7TSHRCASP1 | |
| SCHEMBL8272522 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CHRNA7CASP1 | |
| SCHEMBL9163070 | 0.75 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL4278112 | 0.73 | ALDH1A1 (0.67) | ALDH1A1CHRNA7TSHRCASP1 | |
| SCHEMBL12267516 | 0.71 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL6036829 | 0.69 | ALDH1A1 (0.54) | ALDH1A1CHRNA7TSHRCASP1 | |
| SCHEMBL4877698 | 0.67 | ALDH1A1 (1.00) | ALDH1A1TSHRCASP1 | |
| SCHEMBL31457165 | 0.66 | ALDH1A1 (0.50) | ALDH1A1CHRNA7TSHRCASP1 | |
| SCHEMBL1814854 | 0.65 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL578932 | 0.65 | GAA (0.35) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945309-B | New nitroso compound and application thereof as nitroxyl donors | 卡尔迪奥克斯尔制药公司 | 2019-06-04 | — | — | CN | disclosed |
| US-9732029-B2 | Nitroso compounds as nitroxyl donors and methods of use thereof | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| US-9725402-B2 | Nitroso compounds as nitroxyl donors and methods of use thereof | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| EP-3067352-A2 | NOVEL NITROSO COMPOUNDS AS NITROXYL DONORS AND METHODS OF USE THEREOF | Cardioxyl Pharmaceuticals Inc. (US) | 2016-09-14 | — | — | EP | disclosed |
| EP-2278975-B1 | NOVEL NITROSO COMPOUNDS AS NITROXYL DONORS AND METHODS OF USE THEREOF | CARDIOXYL PHARMACEUTICALS INC (US) | 2016-09-07 | — | — | EP | disclosed |
| US-20160052862-A1 | NOVEL NITROSO COMPOUNDS AS NITROXYL DONORS AND METHODS OF USE THEREOF | CARDIOXYL PHARMACEUTICALS, INC. | 2016-02-25 | — | — | US | disclosed |
| CN-104945309-A | Novel nitroso compounds as nitroxyl donors and methods of use thereof | CARDIOXYL PHARMACEUTICALS INC | 2015-09-30 | — | — | CN | disclosed |
| CN-102076342-B | Novel nitroso compounds as nitroxyl donors and methods of use thereof | CARDIOXYL PHARMACEUTICALS INC | 2015-06-10 | — | — | CN | disclosed |
| US-20140336137-A1 | NOVEL NITROSO COMPOUNDS AS NITROXYL DONORS AND METHODS OF USE THEREOF | CARDIOXYL PHARMACEUTICALS, INC. | 2014-11-13 | — | — | US | disclosed |
| US-8791134-B2 | Nitroso compounds as nitroxyl donors and methods of use thereof | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2014-07-29 | — | — | US | disclosed |
| WO-1998001443-A1 | INDOLE DERIVATIVES FOR THE TREATMENT OF OSTEOPOROSIS | SMITHKLINE BEECHAM S.P.A. (IT) | 1998-01-15 | — | — | WO | disclosed |
| US-5679794-A | ACTINIC LIGHT RESISTANCE, PROCESSING HEAT RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1997-10-21 | — | — | US | disclosed |
| US-5668198-A | Polymer stabilizers containing both hindered amine and hydroxylamine moieties | CIBA-GEIGY CORPORATION (US) | 1997-09-16 | — | — | US | disclosed |
| US-5668199-A | Polymer stabilizers containing both hindered amine and hydroxylamine moieties | CIBA-GEIGY CORPORATION (US) | 1997-09-16 | — | — | US | disclosed |
| US-5410047-A | A 2-hydroxyamino-4,6-substituted triazine as light stabilizers for polymers; radiation resistance, oxidation resistance, discoloration inhibition | CIBA-GEIGY CORPORATION (US) | 1995-04-25 | — | — | US | disclosed |
| EP-0413665-B1 | Polymer stabilizers containing both hindered amine and nitrone moieties | CIBA GEIGY AG (CH) | 1995-04-05 | — | — | EP | disclosed |
| EP-0427672-B1 | POLYMER STABILIZERS CONTAINING BOTH HINDERED AMINE AND HYDROXYLAMINE MOIETIES | CIBA-GEIGY AG (CH) | 1993-09-29 | — | — | EP | disclosed |
| US-5202441-A | Heat resistance, photostability | CIBA-GEIGY CORPORATION (US) | 1993-04-13 | — | — | US | disclosed |
| EP-0427672-A1 | Polymer stabilizers containing both hindered amine and hydroxylamine moieties | CIBA-GEIGY AG (CH) | 1991-05-15 | — | — | EP | disclosed |
| US-4972009-A | PHOTOSTABILIZERS FOR POLYMERS, RADIATION RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1990-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160052862-A1 | NOVEL NITROSO COMPOUNDS AS NITROXYL DONORS AND METHODS OF USE THEREOF | NOXO1, TNNI3, HAO2 | ALDH1A1 624/4885CHRNA7 2820/4885TSHR 3830/4885 |
| US-20140336137-A1 | NOVEL NITROSO COMPOUNDS AS NITROXYL DONORS AND METHODS OF USE THEREOF | NOXO1, TNNI3, HAO2 | ALDH1A1 624/4885CHRNA7 2820/4885TSHR 3830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.