Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 8/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | HCK | P08631 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11141779 | 1.00 | GRM5 (0.42) | GRM5MEN1KMT2AGAALCK | |
| SCHEMBL11155555 | 0.93 | GRM5 (0.46) | GRM5MEN1KMT2AGAANPC1 | |
| SCHEMBL11155554 | 0.93 | GRM5 (0.46) | GRM5MEN1KMT2AGAANPC1 | |
| SCHEMBL11147165 | 0.92 | KMT2A (0.46) | GRM5MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL11147166 | 0.92 | KMT2A (0.46) | GRM5MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL11146311 | 0.87 | GRM5 (0.42) | GRM5MEN1KMT2AGAANPC1 | |
| SCHEMBL11145628 | 0.87 | GRM5 (0.42) | GRM5MEN1KMT2AGAANPC1 | |
| SCHEMBL11150764 | 0.85 | L3MBTL1 (0.55) | KMT2AGAALCKMAPK14MAPK13 | |
| SCHEMBL11148292 | 0.85 | L3MBTL1 (0.41) | GRM5MEN1KMT2AGAAPDK1 | |
| SCHEMBL11144761 | 0.85 | ALDH1A1 (0.44) | GRM5MEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4402964-A | N-Aryl-N'-(3-methyl or ethyl-4-oxothiazolidinylidene)ureas useful for the treatment of epilepsy | MCNEILAB, INC. (US) | 1983-09-06 | — | — | US | disclosed |