Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | ADK | P55263 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 6/20 | 0.43 |
| ▸ | CCND1 | P24385 | 6/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.42 |
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3269364 | 0.92 | KIF11 (0.49) | KIF11BCHEGSK3BADKMAOA | |
| SCHEMBL20293634 | 0.89 | PARP14 (0.48) | KIF11BCHEMAOAHTR2BHTR5A | |
| SCHEMBL30022347 | 0.88 | ESR1 (0.46) | KIF11BCHEMAOAHTR2BHTR5A | |
| SCHEMBL3270153 | 0.88 | MAOA (0.46) | KIF11BCHEMAOAHTR2BHTR5A | |
| SCHEMBL30103587 | 0.88 | MAOA (0.48) | KIF11BCHEMAOAHTR2BHTR5A | |
| SCHEMBL3270151 | 0.88 | MAOA (0.48) | KIF11BCHEMAOAHTR2BHTR5A | |
| SCHEMBL29177864 | 0.87 | KIF11 (0.44) | KIF11BCHEGSK3BADKMAOA | |
| SCHEMBL30022292 | 0.86 | MAOA (0.47) | KIF11BCHEMAOAHTR2BHTR5A | |
| SCHEMBL31276021 | 0.86 | MAOA (0.47) | KIF11BCHEMAOAHTR2BHTR5A | |
| SCHEMBL11145173 | 0.85 | KIF11 (0.54) | KIF11BCHEHTR2BHTR5ATDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4398946-A | Method of homogenizing cast iron melts and compacts for the carrying out thereof | WERNER KESSL GIESSEREIBEDARF GMBH (DE) | 1983-08-16 | — | — | US | claimed |
| EP-0046991-A1 | Process and briquette for homogenizing molten cast iron | Werner Kessl Giessereibedarf GmbH (DE) | 1982-03-10 | — | — | EP | claimed |
| EP-0046991-A1 | Process and briquette for homogenizing molten cast iron | Werner Kessl Giessereibedarf GmbH (DE) | 1982-03-10 | — | — | EP | disclosed |