SCHEMBL3270153

SCHEMBL3270153

c1ccc(-c2cccc(-c3c(-c4ccccc4)ccc4c3[nH]c3ccccc34)c2-c2c(-c3ccccc3)ccc3c2[nH]c2ccccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.46
HTR2B P41595 1/20 0.45
HTR5A P47898 1/20 0.45
TDO2 P48775 1/20 0.45
KIF11 P52732 4/20 0.45
PARP14 Q460N5 4/20 0.44
GABRP O00591 1/20 0.44
GABRD O14764 1/20 0.44
GABRA1 P14867 1/20 0.44
GABRB1 P18505 1/20 0.44
GABRG2 P18507 1/20 0.44
GABRB3 P28472 1/20 0.44
GABRA5 P31644 1/20 0.44
GABRA3 P34903 1/20 0.44
GABRA2 P47869 1/20 0.44
GABRB2 P47870 1/20 0.44
GABRA4 P48169 1/20 0.44
GABRE P78334 1/20 0.44
GABRA6 Q16445 1/20 0.44
GABRG1 Q8N1C3 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30021694 0.96 GABRP (0.44) MAOAHTR2BHTR5ATDO2KIF11
SCHEMBL30022347 0.94 ESR1 (0.46) MAOAHTR2BHTR5ATDO2KIF11
SCHEMBL20293634 0.92 PARP14 (0.48) MAOAHTR2BHTR5ATDO2KIF11
SCHEMBL30103688 0.92 GABRP (0.44) MAOAHTR2BHTR5ATDO2KIF11
SCHEMBL3269364 0.92 KIF11 (0.49) MAOAHTR2BHTR5ATDO2KIF11
SCHEMBL3269690 0.92 KIF11 (0.53) MAOAHTR2BHTR5ATDO2KIF11
SCHEMBL3270151 0.90 MAOA (0.48) MAOAHTR2BHTR5ATDO2KIF11
SCHEMBL30103587 0.90 MAOA (0.48) MAOAHTR2BHTR5ATDO2KIF11
SCHEMBL31276021 0.89 MAOA (0.47) MAOAHTR2BHTR5ATDO2KIF11
SCHEMBL30022292 0.89 MAOA (0.47) MAOAHTR2BHTR5ATDO2KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118339941-A Mixed powder and method for producing same, method for producing organic electroluminescent element using same, method for selecting compound in mixed powder, and composition for vacuum vapor deposition 出光兴产株式会社 2024-07-12 CN disclosed
CN-117616909-A Mixed powder for organic electroluminescent element and method for producing same, method for producing organic electroluminescent element using same, method for selecting compound in mixed powder, and composition for vacuum evaporation 出光兴产株式会社 2024-02-27 CN disclosed
CN-117581654-A Mixed powder, mixed body, and method for manufacturing organic electroluminescent element 出光兴产株式会社 2024-02-20 CN disclosed
US-8343637-B2 Carbazole derivatives for organic electroluminescent devices MERCK PATENT GMBH (DE) 2013-01-01 US disclosed
EP-2102309-B1 CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2010-06-30 EP disclosed
US-20090302752-A1 CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2009-12-10 US disclosed
EP-2102309-A1 CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2009-09-23 EP disclosed
WO-2008086851-A1 CARBAZOLE DERIVATIVES FOR ORGANC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2008-07-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090302752-A1 CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES PIEZO1, CACNA2D1, CYCS MAOA 1221/4885HTR2B 2741/4885HTR5A 3115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.