Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11145174 | 0.92 | KIF11 (0.54) | KIF11BCHEGABRPGABRDGABRA1 | |
| SCHEMBL3270153 | 0.92 | MAOA (0.46) | KIF11BCHEGABRPGABRDGABRA1 | |
| SCHEMBL30021694 | 0.91 | GABRP (0.44) | KIF11BCHEGABRPGABRDGABRA1 | |
| SCHEMBL30103688 | 0.87 | GABRP (0.44) | KIF11BCHEGABRPGABRDGABRA1 | |
| SCHEMBL3269690 | 0.87 | KIF11 (0.53) | KIF11GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28898940 | 0.86 | KIF11 (0.57) | KIF11BCHEGABRPGABRDGABRA1 | |
| SCHEMBL30022347 | 0.86 | ESR1 (0.46) | KIF11BCHEGABRPGABRDGABRA1 | |
| SCHEMBL3269361 | 0.86 | KIF11 (0.57) | KIF11BCHEGABRPGABRDGABRA1 | |
| SCHEMBL29177864 | 0.85 | KIF11 (0.44) | KIF11BCHEGABRPGABRDGABRA1 | |
| SCHEMBL30022713 | 0.85 | BCHE (0.42) | KIF11BCHEGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8343637-B2 | Carbazole derivatives for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2013-01-01 | — | — | US | disclosed |
| EP-2102309-B1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-06-30 | — | — | EP | disclosed |
| US-20090302752-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
| EP-2102309-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008086851-A1 | CARBAZOLE DERIVATIVES FOR ORGANC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2008-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090302752-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, CACNA2D1, CYCS | KIF11 3273/4885BCHE 3730/4885GABRP 1640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.