Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1422386 | 0.87 | GAA (0.74) | LMNAGAAALDH1A1L3MBTL1POLB | |
| SCHEMBL6594783 | 0.85 | LMNA (0.64) | LMNAGAAALDH1A1L3MBTL1POLB | |
| SCHEMBL7893624 | 0.85 | LMNA (0.57) | LMNAGAAALDH1A1L3MBTL1POLB | |
| SCHEMBL11148867 | 0.85 | TDP1 (0.66) | LMNAGAAALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL1807728 | 0.85 | LMNA (0.60) | LMNAGAAALDH1A1L3MBTL1POLB | |
| SCHEMBL7358861 | 0.85 | LMNA (0.60) | LMNAGAAALDH1A1L3MBTL1POLB | |
| SCHEMBL17114436 | 0.82 | MAPK1 (0.65) | LMNAGAAALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL7904262 | 0.81 | ALDH1A1 (0.70) | LMNAGAAALDH1A1L3MBTL1POLB | |
| SCHEMBL1807729 | 0.81 | ALDH1A1 (0.58) | LMNAGAAALDH1A1L3MBTL1POLB | |
| SCHEMBL17117499 | 0.81 | GAA (0.59) | LMNAGAAALDH1A1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0091749-A2 | Ethanolamine derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1983-10-19 | — | — | EP | disclosed |