Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11144383 | 0.77 | KDR (0.37) | PARP15PARP10TNKS2PARP2PDE10A | |
| SCHEMBL11149355 | 0.64 | LIMK1 (0.45) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL10586695 | 0.62 | CYP3A4 (0.50) | PARP15PARP10TNKS2PARP2PDE3A | |
| SCHEMBL13899583 | 0.62 | ALDH1A1 (0.47) | KDRSMN1; SMN2ALDH1A1CYP3A4SCN9A | |
| SCHEMBL11331479 | 0.62 | LIMK1 (0.51) | — | |
| Bromide SCHEMBL10584554 | 0.61 | CYP3A4 (0.49) | PARP15PARP10TNKS2PARP2PDE3A | |
| Hydrochloric Acid SCHEMBL10585624 | 0.61 | CYP3A4 (0.49) | PARP15PARP10TNKS2PARP2PDE3A | |
| SCHEMBL16006484 | 0.61 | CYP19A1 (0.41) | CYP19A1NQO2SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL1122691 | 0.59 | TUBB4A (0.55) | CYP19A1SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL26672527 | 0.59 | ACHE (0.39) | CYP19A1NQO2PARP15PARP10TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005357-A1 | N-(Benzothienopyrazol)-amides and pharmaceutical compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-11-14 | — | — | EP | disclosed |