Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.44 |
| ▸ | MAPT | P10636 | 10/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21488500 | 0.88 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDL3MBTL1TDP1 | |
| SCHEMBL11149035 | 0.78 | ALDH1A1 (0.69) | ALDH1A1MAPTHPGDL3MBTL1TDP1 | |
| SCHEMBL11148915 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDL3MBTL1TDP1 | |
| SCHEMBL11147987 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDL3MBTL1TDP1 | |
| SCHEMBL11147982 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDL3MBTL1TDP1 | |
| Hydrochloric Acid SCHEMBL9094970 | 0.70 | DRD2 (0.48) | ALDH1A1TSHRLMNAPOLBALDH3A1 | |
| Hydrochloric Acid SCHEMBL11149567 | 0.69 | DRD2 (0.58) | ALDH1A1NPSR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11154283 | 0.67 | CHRM5 (0.53) | ALDH1A1MAPTHPGDL3MBTL1TDP1 | |
| SCHEMBL11148681 | 0.67 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDL3MBTL1TDP1 | |
| SCHEMBL20504718 | 0.66 | HPGD (0.43) | ALDH1A1MAPTHPGDL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4382934-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
| EP-0010398-B1 | ISATIN DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-27 | — | — | EP | disclosed |
| EP-0010398-A1 | Isatin derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-04-30 | — | — | EP | disclosed |