Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.52 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10440174 | 0.86 | EPHX1 (0.50) | SIGMAR1TAAR1SLC18A2TRPA1SLC6A2 | |
| SCHEMBL23715790 | 0.83 | TAAR1 (0.57) | SIGMAR1TAAR1SLC18A2TRPA1SLC6A2 | |
| SCHEMBL3403178 | 0.80 | TRPA1 (0.55) | SIGMAR1TAAR1SLC18A2TRPA1SLC6A2 | |
| SCHEMBL474146 | 0.80 | TAAR1 (0.59) | SIGMAR1TAAR1SLC18A2TRPA1SLC6A2 | |
| Diphenylmethane SCHEMBL9322451 | 0.80 | CALM1 (0.55) | SIGMAR1TAAR1SLC18A2TRPA1SLC6A2 | |
| SCHEMBL995916 | 0.79 | MME (0.56) | NPC1RAB9A | |
| SCHEMBL18515374 | 0.79 | SIGMAR1 (0.47) | SIGMAR1TAAR1TRPA1SLC6A2MAOA | |
| SCHEMBL14519203 | 0.79 | TAAR1 (0.52) | SIGMAR1TAAR1SLC18A2TRPA1SLC6A2 | |
| SCHEMBL9812081 | 0.77 | SIGMAR1 (0.59) | SIGMAR1TAAR1SLC18A2SLC6A2SLC6A3 | |
| SCHEMBL3936936 | 0.77 | CYP1A2 (0.46) | SIGMAR1TAAR1SLC18A2TRPA1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4408072-A | Amido methoxyethylamines | AMERICAN CYANAMID COMPANY (US) | 1983-10-04 | — | — | US | disclosed |
| US-4314079-A | Novel methoxyethylamine | AMERICAN CYANAMID COMPANY (US) | 1982-02-02 | — | — | US | disclosed |
| US-4245103-A | Processes for the preparation of tetramisole | AMERICAN CYANAMID COMPANY (US) | 1981-01-13 | — | — | US | disclosed |