Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11154823 | 0.88 | POLB (0.46) | POLBL3MBTL1ALDH1A1LMNAMAPT | |
| SCHEMBL11149155 | 0.83 | POLB (0.42) | POLBL3MBTL1ALDH1A1LMNAMAPT | |
| SCHEMBL11152267 | 0.77 | LMNA (0.41) | POLBL3MBTL1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11148775 | 0.73 | ALDH1A1 (0.52) | POLBALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL11154687 | 0.73 | LMNA (0.46) | POLBALDH1A1LMNANPC1HPGD | |
| SCHEMBL11148605 | 0.71 | ALDH1A1 (0.55) | POLBALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL11146570 | 0.70 | LMNA (0.41) | POLBALDH1A1LMNAMAPTHTT | |
| SCHEMBL11154817 | 0.67 | MAPK8 (0.47) | ALDH1A1LMNAMAPTCNR2KDM4E | |
| SCHEMBL2343009 | 0.67 | ALDH1A1 (0.70) | POLBALDH1A1LMNAMAPTHSP90AA1 | |
| SCHEMBL27249840 | 0.67 | HTR3A (0.63) | POLBL3MBTL1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379929-A | BACTERIOSTATS | ELI LILLY AND COMPANY (US) | 1983-04-12 | — | — | US | disclosed |