Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11149155 | 0.87 | POLB (0.42) | LMNAALDH1A1KDM4ETSHRBLM | |
| SCHEMBL11154823 | 0.87 | POLB (0.46) | LMNAALDH1A1KDM4ETSHRBLM | |
| SCHEMBL11154817 | 0.86 | MAPK8 (0.47) | LMNAALDH1A1KDM4ETSHRBLM | |
| SCHEMBL11143530 | 0.82 | ALDH1A1 (0.51) | LMNAALDH1A1KDM4ETSHRBLM | |
| SCHEMBL11150628 | 0.82 | TSHR (0.64) | LMNAALDH1A1KDM4ETSHRBLM | |
| SCHEMBL11149089 | 0.81 | ALDH1A1 (0.71) | LMNAALDH1A1KDM4ETSHRBLM | |
| SCHEMBL11146570 | 0.78 | LMNA (0.41) | LMNAALDH1A1KDM4ETSHRBLM | |
| SCHEMBL11152249 | 0.74 | KDM4E (0.40) | LMNAALDH1A1KDM4ETSHRBLM | |
| SCHEMBL11147216 | 0.74 | ADORA2A (0.43) | LMNAALDH1A1KDM4ETSHRBLM | |
| SCHEMBL11148179 | 0.73 | POLB (0.43) | LMNAALDH1A1KDM4EHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379929-A | BACTERIOSTATS | ELI LILLY AND COMPANY (US) | 1983-04-12 | — | — | US | disclosed |