Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11147547 | 0.89 | BTK (0.40) | POLBALDH1A1KMT2ALMNAL3MBTL1 | |
| SCHEMBL11446079 | 0.88 | KCNH2 (0.43) | KCNH2POLBALDH1A1KMT2ALMNA | |
| SCHEMBL11148240 | 0.76 | OPRD1 (0.42) | POLBALDH1A1KMT2ALMNAL3MBTL1 | |
| SCHEMBL11148698 | 0.76 | KCNH2 (0.40) | KCNH2KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11148693 | 0.76 | KCNH2 (0.40) | KCNH2KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11149274 | 0.76 | POLB (0.43) | KCNH2POLBKMT2ALMNAL3MBTL1 | |
| SCHEMBL11247290 | 0.74 | NPSR1 (0.55) | KCNH2POLBALDH1A1KMT2ALMNA | |
| SCHEMBL11439872 | 0.74 | KCNH2 (0.43) | KCNH2ALDH1A1KMT2ALMNAL3MBTL1 | |
| SCHEMBL11248409 | 0.73 | ALDH1A1 (0.54) | KCNH2POLBALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL11151507 | 0.73 | KMT2A (0.44) | KCNH2POLBALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009683-A1 | Basic phenyl ethers, pharmaceutical compositions containing them and the preparation of these ethers and compositions | MERCK PATENT GmbH (DE) | 1980-04-16 | — | — | EP | disclosed |