Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11439870 | 0.89 | KCNH2 (0.39) | KMT2AALDH1A1POLBLMNAL3MBTL1 | |
| SCHEMBL11148240 | 0.87 | OPRD1 (0.42) | BTKKMT2AALDH1A1POLBMEN1 | |
| SCHEMBL11446079 | 0.76 | KCNH2 (0.43) | KMT2AALDH1A1POLBLMNAL3MBTL1 | |
| SCHEMBL11148132 | 0.75 | POLB (0.44) | BTKKMT2APOLBMEN1NPC1 | |
| SCHEMBL11439742 | 0.74 | ALDH1A1 (0.48) | BTKKMT2AALDH1A1POLBP2RX7 | |
| SCHEMBL11144905 | 0.74 | TBXAS1 (0.52) | KMT2A | |
| Hydrochloric Acid SCHEMBL11433492 | 0.74 | POLB (0.43) | BTKKMT2APOLBMEN1NPC1 | |
| SCHEMBL11155733 | 0.74 | OPRD1 (0.37) | POLBLMNAL3MBTL1TNK2RELA | |
| SCHEMBL11147568 | 0.73 | BTK (0.39) | BTKKMT2AMEN1NPC1LMNA | |
| SCHEMBL11151601 | 0.72 | KMT2A (0.44) | KMT2AALDH1A1POLBP2RX7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009683-B1 | BASIC PHENYL ETHERS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THE PREPARATION OF THESE ETHERS AND COMPOSITIONS | MERCK PATENT GmbH (DE) | 1983-08-10 | — | — | EP | disclosed |
| EP-0009683-A1 | Basic phenyl ethers, pharmaceutical compositions containing them and the preparation of these ethers and compositions | MERCK PATENT GmbH (DE) | 1980-04-16 | — | — | EP | disclosed |