Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 4/20 | 0.46 |
| ▸ | SNCA | P37840 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11147292 | 0.82 | MAPT (0.50) | METAP1MAPTKMT2AMEN1AMY1A | |
| SCHEMBL11149380 | 0.81 | METAP1 (0.49) | METAP1MAPTKMT2AMEN1AMY1A | |
| SCHEMBL11142869 | 0.81 | MAPT (0.51) | METAP1MAPTKMT2AMEN1AMY1A | |
| SCHEMBL11153981 | 0.77 | ERBB2 (0.60) | MAPTKMT2AMEN1AMY1AALDH1A1 | |
| SCHEMBL11146554 | 0.77 | CISD1 (0.58) | MAPTKMT2AMEN1AMY1AALDH1A1 | |
| SCHEMBL11146269 | 0.77 | MEN1 (0.58) | METAP1MAPTKMT2AMEN1AMY1A | |
| SCHEMBL16979817 | 0.76 | EP300 (0.66) | MAPTKMT2AMEN1ALDH1A1CA12 | |
| SCHEMBL14680297 | 0.74 | NOX4 (0.52) | MAPTKMT2AMEN1ALDH1A1CA12 | |
| SCHEMBL25526234 | 0.73 | MAPT (0.47) | MAPTKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL11151011 | 0.73 | TDP1 (0.47) | MAPTKMT2AMEN1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4389477-A | Photoconductive composition sensitized by a thiobarbituric acid derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1983-06-21 | — | — | US | disclosed |